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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
GLG1 Self-glycosylating initiator of glycogen synthesis 
Entry:YKR058w
Classification:known protein | 5422 Entries
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (26.1 %) ;  |  Homologs in   Hemiascomycota (76.8 %);  Basidiomycota (16.5 %);  Fungi (76.8 %);  Eukaryota (76.8 %);  Plants (12.8 %);  Mammalia (20.4 %);  Human (20.4 %);  Bacteria (17.2 %);  All except yeast (76.8 %)

  • similarity to Glg2p, weak similarity to mammalian glycogenin
Functional Classification:
  • METABOLISM
    ..C-compound and carbohydrate metabolism
    ....polysaccharide metabolism
    ......glycogen metabolism
    ........glycogen anabolism | 5 Entries | Evi | PUBMED
  • ENERGY
    ..metabolism of energy reserves (e.g. glycogen, trehalose) | 56 Entries | Evi
EC Number:
  • 2.4.1.186: Transferases
    ..Glycosyltransferases
    ....Hexosyltransferases
    ......glycogenin glucosyltransferase | 2 Entries | Evi | PUBMED
InterPro:
Localization:  GLG1 localization details
  • cytoplasm
 TargetP: Secretory pathway  (RC = 4)
Remarks:
  • by homology to hemiascomycetous yeasts this orf can be extended for 131 aa N-terminal | PUBMED
  • sequence should be 618 aa long - two frame
  • Due to a insertion of G at position 552427 after G and a deletion of A at position 552523 after A, confirmed by genomic PCR in S288C the coordinates of YKR058w/GLG1 changed from 552820 - 554262 to 552412 - 554262. 1851nt (616aa). | Evi | PUBMED
    Phenotypes:  Disruption: GLG1 details
    • viable
    ___
    • glg1 glg2 double null mutant is unable to synthesize glycogen
    • in glg1 glg2 double null mutants, glycogen synthase activity is suppressed
    Click for larger Map
    Physical Features
    Coordinates:552412 - 554262 (W)
    Length:1851 nt
    Contig:chrXI
    Exon Coordinates:552412 - 554262
    GC Content:39.2 %
    Protein Length:480 aa
    Isoelectric Point:4.14
    Molecular Weight:54333 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z28283
    PIR: S38134
    NCBI: NP_012984
    Additional Links:
    CYGD Pathways:
  • Metabolic and genetic control of gene expression
  • CYGD Tables:
  • Transcriptional map of chromosome XI
  • LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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