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(chrI - chrXVI,chrMito,2-micron)

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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
TIM8 Delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex 
Entry:YJR135w-a
Classification:known protein | 5422 Entries
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (23 %) ;  |  Homologs in   Hemiascomycota (97.7 %);  Basidiomycota (43.7 %);  Fungi (97.7 %);  Eukaryota (97.7 %);  Plants (27.6 %);  Mammalia (35.1 %);  Human (34 %);  Bacteria (21.8 %);  All except yeast (97.7 %)

    Functional Classification:
    • PROTEIN FATE (folding, modification, destination)
      ..protein targeting, sorting and translocation | 280 Entries | Evi | PUBMED
    • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
      ..transport routes
      ....mitochondrial transport | 104 Entries | Evi | PUBMED
    • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
      ..transported compounds (substrates)
      ....protein transport | 140 Entries | Evi | PUBMED
    Pathway:
    • mitochondrial protein import | in Tim8-9-13-complex | PUBMED
    TC Class:
    • The Driven Transporters
      ..The P-P Bond Hydrolysis - Driven Transporters
      ....The Mitochondrial Protein Translocase (MPT) Family
      ......The Inner Mitochondrial Membrane Protein Translocase (TIM) Subfamily | 12 Entries | Evi | PUBMED
    InterPro:
    Localization:  TIM8 localization details
    • mitochondria
    • mitochondria
      ..mitochondrial intermembrane space
    Remarks:
      • Cysteine spacing: H2N-43-C-3-C-15-C-3-C-19-COOH
    Phenotypes:  Disruption: TIM8 details
    • viable
    ___
    • lack of the Tim8-13 complex
    Click for larger Map
    Physical Features
    Coordinates:676965 - 677228 (W)
    Length:264 nt
    Contig:chrX
    Exon Coordinates:676965 - 677228
    GC Content:37.5 %
    Protein Length:87 aa
    Isoelectric Point:5.24
    Molecular Weight:9764 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z49635
    UniProtKB: P57744
    NCBI: NP_058168
    Additional Links:
    CYGD Tables:
  • The Yeast homologues of human disease-associated genes
  • LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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