| Entry: | YJL129c |
| Alias: | J0693 |
| Classification: | known protein | 5422 Entries |
| Feature Type: | CDS |
| Features |
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Blast-Simap
DNA VIEW
PROTEIN VIEW
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| Similarity: |
similarity to Trk2p, and S.pombe potassium transport protein homologmember of the potassium permease family of the major facilitator superfamily |
| Functional Classification: | - INTERACTION WITH THE ENVIRONMENT
..homeostasis ....homeostasis of cations ......homeostasis of metal ions (Na, K, Ca etc.)
| 98 Entries | Evi
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PUBMED
- CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
..transport routes ....cellular import
| 150 Entries | Evi
- CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
..transported compounds (substrates) ....ion transport ......cation transport (H+, Na+, K+, Ca2+ , NH4+, etc.)
| 122 Entries | Evi
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PUBMED
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| TC Class: | - The Uni/Sym/Antiporters
..The Uni/Sym/Antiporters ....The K+ Transporter (TRK) Family ......The K+ Transporter (TRK-2) Subfamily Type2 | 2 Entries |
Evi
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PUBMED
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InterPro:
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| Localization: | TRK1 localization details TargetP: Mitochondrion
(RC = 3)
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| Remarks: | potassium uptake (Trk1p plus Trk2p activity) is activated by glucose and other fermentable sugars and by cytoplasmic acidification or by neomycin |
PUBMED
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| Phenotypes: | Disruption: TRK1 details___
trk1 trk2 double null mutants are hypersensitive to channel blocker 4-aminopyridine |
PUBMED
trk1 trk2 double mutant show normal growth on media containing 100 mM K+, slow growth with 7 mM K+ and no growth with 0.2 mM K+trk1 trk2 double mutant show no growth on pH 3.0 |
PUBMED
Exhibits sensitivity at 5 generations when grown in 1 M NaCl. | Evi
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PUBMED
Exhibits sensitivity at 5 generations when grown in minimal +his/leu/ura medium. | Evi
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PUBMED
Exhibits sensitivity at 5 generations when grown in synthetic complete medium. | Evi
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PUBMED
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| Suppression: | trk1 trk2 double null mutant can be suppressed on K+-limiting medium by gain-of function mutations of HXT1, HXT3 or GAL2 |
PUBMED
the suppression of trk1 trk2 double null mutant by HXT1, HXT3 or GAL2 gain-of-function mutants is dependent on glucose |
PUBMED
Arabidopsis KAT1 overexpression confer normal growth to trk1 trk2 double mutanthip1-293 mutation F293 to S |
PUBMED
trk1 trk2 double null mutant can be suppressed by HOL1-1 dominant mutation |
PUBMED
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