GSFLogo GSF

 

mipsLogo mips
GenRE
Search ORF/Gene/Description

Chromosome
(chrI - chrXVI,chrMito,2-micron)

Catalogs:
Chromosome View
  I  II  III  IV  V  VI  VII
  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
Other

Search / View

   Advanced Search

   Index Search

MPact protein interaction

Tables, Lists and Reviews

WUBLAST DNA/Protein

About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
BNR1 Regulator of budding 
Entry:YIL159w
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (16.7 %) ;  |  Homologs in   Hemiascomycota (90 %);  Basidiomycota (18 %);  Fungi (90 %);  Eukaryota (90 %);  Plants (16.5 %);  Mammalia (18.3 %);  Human (18.2 %);  Bacteria (16.8 %);  All except yeast (90 %)

  • similarity to Bni1p, E.nidulans regulatory protein, fruit fly diaphanous and cappuccino protein and chicken limb deformity protein
Functional Classification:
  • CELL RESCUE, DEFENSE AND VIRULENCE
    ..stress response
    ....osmotic and salt stress response | 59 Entries | Evi | PUBMED
  • CELL TYPE DIFFERENTIATION
    ..fungal/microorganismic cell type differentiation
    ....fungal and other eukaryotic cell type differentiation
    ......budding, cell polarity and filament formation | 313 Entries | Evi | PUBMED
  • BIOGENESIS OF CELLULAR COMPONENTS
    ..cytoskeleton/structural proteins
    ....actin cytoskeleton | 96 Entries | Evi | PUBMED
  • PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
    ..protein binding | 392 Entries | Evi | PUBMED
InterPro:
Localization:  BNR1 localization details
  • bud
    ..neck
  • cell periphery
  • cytoskeleton
  • cytoskeleton
    ..actin cytoskeleton
Remarks:
  • maybe required for localization of axial positional signals to the presumptive budding site | PUBMED
  • contains FH1 domain (aa-position 768-850) and FH2 domain (aa-domains 1037-1163) | PUBMED
  • interaction of Bnr1p and Pfy1 is via FH1 domain | PUBMED
  • Bnr1p do not interact with Rho2p, Rho3p and Cdc42p in two hybrid experiments | PUBMED
  • Bnr1p binds preferentially to the GTP-bound form of Rho4 | PUBMED
Phenotypes:  Disruption: BNR1 details
  • viable
___
  • bni1 deletion mutant shows no phenotype | PUBMED
  • bni1 bnr1 double mutant shows ts growth phenotype | PUBMED
  • bni1 bnr1 double mutant shows deficiency in bud emergence | PUBMED
  • bni1 bnr1 double mutant shows random distribution of cortical actin patches | PUBMED
  • bni1 bnr1 double mutant shows often multinucleation | PUBMED
Click for larger Map
Physical Features
Coordinates:41825 - 45952 (W)
Length:4128 nt
Contig:chrIX
Exon Coordinates:41825 - 45952
GC Content:36.1 %
Protein Length:1375 aa
Isoelectric Point:8.05
Molecular Weight:156853 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z38059
EMBL: Z47047
PIR: S48375
UniProtKB: P40450
NCBI: NP_012107
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

  • To submit new information about this entry, please write to

    © 2003 GSF - Forschungszentrum für Umwelt und Gesundheit, GmbH Ingolstädter Landstraße 1, D-85764 Neuherberg

    Imprint

    Disclaimer:
    MIPS Databases and associated information are protected by copyright. This server and its associated data and services are for academic, non-commercial use only. The GSF has no liability for the use of results, data or information which have been provided through this server. Neither the use for commercial purposes, nor the redistribution of MIPS database files to third parties nor the distribution of parts of files or derivative products to any third parties is permitted. Commercial users may contact the distributor Biomax Informatics AG.