| Entry: | YIL118w |
| Classification: | known protein | 5422 Entries | Evi
|
PUBMED
|
| Feature Type: | CDS |
| Features |
 |
Blast-Simap
DNA VIEW
PROTEIN VIEW
|
| Similarity: |
strong similarity to Rho1p, S.pombe Rho1, mammalian rhoA,B,C and other GTP-binding proteins of the rho family |
| Functional Classification: | - CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
..transport routes
....cellular export and secretion
......vesicular cellular export
........exocytosis
| 33 Entries | Evi
|
PUBMED
- CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM
..cellular signalling
....enzyme mediated signal transduction
......G-protein mediated signal transduction
........small GTPase mediated signal transduction
| 58 Entries | Evi
|
PUBMED
- CELL TYPE DIFFERENTIATION
..fungal/microorganismic cell type differentiation
....fungal and other eukaryotic cell type differentiation
......budding, cell polarity and filament formation
| 313 Entries | Evi
|
PUBMED
- BIOGENESIS OF CELLULAR COMPONENTS
..cytoskeleton/structural proteins
....actin cytoskeleton
| 96 Entries | Evi
|
PUBMED
|
|
InterPro:
| |
| Localization: | RHO3 localization details |
| Phenotypes: | Disruption: RHO3 details___
dominant rho3(Ala119) mutant is cold-sensitivedominant alleles can be constructed analogous to human H-ras (Val-12) and H-ras(Ala119) mutationsnull mutant has severe growth delay and decrease in viabilitynull mutant growth defect is suppressed by overproduction of Rho4pts mutant is not defective in secretion of invertase ___
Conditional phenotypes
..Heat-sensitivity (ts) | 313 Entries Conditional phenotypes
..Cold-sensitivity (cs) | 105 Entries Conditional phenotypes
..Slow-growth (slg) | 237 Entries |
| Overexpression: | overproduction of Sec4p suppresses temperature-sensitive mutants |
| Suppression: | SRO4 is a multicopy suppressor of rho3dominant cold-sensitivity of rho3(Ala119) mutant can be suppressed by ts sec4 mutant but not by other sec mutants |
