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Chromosome
(chrI - chrXVI,chrMito,2-micron)

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About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
ARO9 Aromatic amino acid aminotransferase II 
Entry:YHR137w
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (29.8 %) ;  |  Homologs in   Hemiascomycota (95.3 %);  Basidiomycota (28.5 %);  Fungi (95.3 %);  Eukaryota (95.3 %);  Plants (18.3 %);  Mammalia (26.3 %);  Human (25.5 %);  Bacteria (24.9 %);  All except yeast (95.3 %)
  • similarity to ARO8, rat kynurenine/alpha-aminoadipate aminotransferase
Functional Classification:
  • METABOLISM
    ..amino acid metabolism
    ....metabolism of the cysteine - aromatic group
    ......metabolism of phenylalanine | 17 Entries | Evi | PUBMED
  • METABOLISM
    ..amino acid metabolism
    ....metabolism of the cysteine - aromatic group
    ......metabolism of tyrosine | 16 Entries | Evi | PUBMED
  • METABOLISM
    ..amino acid metabolism
    ....metabolism of the cysteine - aromatic group
    ......metabolism of tryptophan | 20 Entries | Evi | PUBMED
  • METABOLISM
    ..amino acid metabolism
    ....regulation of amino acid metabolism | 33 Entries | Evi
  • METABOLISM
    ..secondary metabolism
    ....metabolism of secondary products derived from primary amino acids
    ......metabolism of alkaloids | 2 Entries | Evi | PUBMED
EC Number:
  • 2.6.1.57: Transferases
    ..Transferring Nitrogenous Groups
    ....Transaminases
    ......aromatic-amino-acid transaminase | 2 Entries | Evi | PUBMED
InterPro:
Localization:  ARO9 localization details
  • cytoplasm
  • nucleus
Remarks:
  • difference between U10398 and Y13625 in aa position 460 (V -> L)
  • ARO9 expression is induced when aromatic acids are present in the growth medium and also in aro8 mutants grown on minimal ammonia medium | PUBMED
    Phenotypes:  Disruption: ARO9 details
    • viable
    ___
    • aro8 aro9 double mutant cannot grow on minimal medium supplemented with ammonia, tryptophane, kinurenine, phenylalanine, tyrosine and methionine | PUBMED
    • aro9 mutant show slow growth phenotype on minimal medium supplemented with tryptophane and kinurenine | PUBMED
    • aro9 mutant do not display inducible tryptophan:phenylpyruvate activity | PUBMED
    ___
    Click for larger Map
    Physical Features
    Coordinates:375712 - 377253 (W)
    Length:1542 nt
    Contig:chrVIII
    Exon Coordinates:375712 - 377253
    GC Content:40.7 %
    Protein Length:513 aa
    Isoelectric Point:5.33
    Molecular Weight:58527.7 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: U10398
    EMBL: Y13625
    PIR: S48981
    NCBI: NP_012005
    Additional Links:
    LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
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