| Entry: | YHR118c |
| Alias: | (AAP1) |
| Classification: | known protein | 5422 Entries | Evi
|
PUBMED
|
| Feature Type: | CDS |
| Features |
 |
Blast-Simap
DNA VIEW
PROTEIN VIEW
|
| Similarity: |
|
| Functional Classification: | - INTERACTION WITH THE ENVIRONMENT
..cellular sensing and response to external stimulus
....chemoperception and response
......pheromone response, mating-type determination, sex-specific proteins
| 189 Entries | Evi
- CELL CYCLE AND DNA PROCESSING
..DNA processing
....DNA synthesis and replication
......ori recognition and priming complex formation
| 25 Entries | Evi
|
PUBMED
- CELL CYCLE AND DNA PROCESSING
..DNA processing
....DNA restriction or modification
......DNA conformation modification (e.g. chromatin)
| 187 Entries | Evi
|
PUBMED
- TRANSCRIPTION
..RNA synthesis
....mRNA synthesis
......transcriptional control
| 495 Entries | Evi
|
|
InterPro:
| |
| Localization: | ORC6 localization details |
| Remarks: | phosphorylated when cells enter S-phase |
PUBMED
|
| Phenotypes: | Disruption: ORC6 details___
mutants arrest without initiating replicationmutants defective in minichromosome maintenance in ARS-specific mannerno phosphorylated Cdc6p detected in cells with mutation of all potential Cdc28 phopshorylation sites |
PUBMED
___
Cell cycle defects
..other cell cycle defects | 207 Entries Nucleic acid metabolism defects
..DNA replication mutants
....other DNA replication mutants | 19 Entries |
| Overexpression: | overproduction exacerbates the phenotypes of cdc6 and cdc46 mutationsoverproduction causes synthetic dosage lethality in combination with recplication mutants cdc2-1, cdc6-1, cdc14-1, cdc16-1, and cdc46-1overproduction causes synthetic slow growth phenotype in ctf19-26 at 37Coverproduction causes synthetic slow growth phenotype in cdc23-1 at 25Coverproduction causes synthetic slow growth phenotype in cdc27-1 at 30C |
