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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
COX6 Cytochrome-c oxidase subunit VI 
Entry:YHR051w
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (9.6 %) ;  |  Homologs in   Hemiascomycota (95.9 %);  Basidiomycota (48.6 %);  Fungi (95.9 %);  Eukaryota (95.9 %);  Plants (14 %);  Mammalia (38 %);  Human (37.3 %);  Bacteria (18.9 %);  All except yeast (95.9 %)

  • similarity to mammalian cytochrome-c oxidase subunit Va
Functional Classification:
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transported compounds (substrates)
    ....electron transport | 83 Entries | Evi | PUBMED
EC Number:
  • 1.9.3.1: Oxidoreductases
    ..Acting on a heme group of donors
    ....With oxygen as acceptor
    ......cytochrome-c oxidase | 12 Entries | Evi | PUBMED
Pathway:
  • oxidative phosphorylation;respiratory chain | terminal component of the respiratory chain
TC Class:
  • The Driven Transporters
    ..The Oxidoreduction-driven Active Transporters
    ....The Proton-translocating Cytochrome Oxidase (COX) Superfamily
    ......The Mitochondrial Cytochrome Oxidase Subfamily | 12 Entries | Evi | PUBMED
InterPro:
Localization:  COX6 localization details
  • mitochondria
 TargetP: Mitochondrion  (RC = 2)
 Mitop2:  Mitochondrial probability - 98  %
Remarks:
    • lacks methionine
Phenotypes:  Disruption: COX6 details
  • viable
___ ___
  • Stress response defects
    ..Oxidizing agents
    ....H2O2
    ......H2O2 sensitivity | 18 Entries
Click for larger Map
Physical Features
Coordinates:209699 - 210145 (W)
Length:447 nt
Contig:chrVIII
Exon Coordinates:209699 - 210145
GC Content:38.7 %
Protein Length:148 aa
Isoelectric Point:5.8
Molecular Weight:17341.6 Da
Mature Protein:see | Evi | PUBMED
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: U00062
PIR: A22853
UniProtKB: P00427
NCBI: NP_011918
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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