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Chromosome
(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
SPO13 Meiosis-specific protein 
Entry:YHR014w
Classification:known protein | 5422 Entries
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (20.3 %) ;  |  Homologs in   Hemiascomycota (89.7 %);  Basidiomycota (15.1 %);  Fungi (89.7 %);  Eukaryota (89.7 %);  Plants (18.6 %);  Mammalia (16.1 %);  Human (19.3 %);  Bacteria (18.9 %);  All except yeast (89.7 %)

    Functional Classification:
    • CELL CYCLE AND DNA PROCESSING
      ..DNA processing
      ....DNA restriction or modification
      ......DNA conformation modification (e.g. chromatin) | 187 Entries | Evi | PUBMED
    • PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
      ..protein binding | 392 Entries | Evi | PUBMED
    • CELL CYCLE AND DNA PROCESSING
      ..cell cycle
      ....nuclear and chromosomal cycle
      ......chromosome condensation | 22 Entries | Evi | PUBMED
    Localization:  SPO13 localization details
    • nucleus
     TargetP: Mitochondrion  (RC = 3)
    Remarks:
    • aberant expression of Spo13, Spo11, Ssa1 and other early meiotic genes in mitotic cells with mutated SSN8 | PUBMED
      Phenotypes:  Disruption: SPO13 details
      • viable
      ___
      • performs a single division in meiosis producing two diploid spores
      • in a sir3 spo13 mutant haploid cells perform a single division in meiosis producing two haploid spores
      • Ssn8p mutants resistant to degradation result in 2-fold decreased SPO13 mRNA levels during meiose | PUBMED
      • in sir3 spo13 mutants spore viability is ~19%, in the meiotic division unequal sister chromatid recombination takes place
      ___
      • Mating and sporulation defects
        ..Sporulation efficiency | 112 Entries
      Click for larger Map
      Physical Features
      Coordinates:132040 - 132915 (W)
      Length:876 nt
      Contig:chrVIII
      Exon Coordinates:132040 - 132915
      GC Content:37.2 %
      Protein Length:291 aa
      Isoelectric Point:9.59
      Molecular Weight:33294.6 Da
      Retrieve Sequence: DNA /Protein
      Literature | References
      CYGD curated Lit.:PubMed
      PubMed:Search abstracts
      PubMed Central:Search full-text articles
      Sequence References:
      EMBL: M38357
      PIR: A38426
      UniProtKB: P23624
      NCBI: NP_011878
      Additional Links:
      LinkOut:
    • SGD - Saccharomyces Genome Database
    • YGOB - Yeast Gene Order Browser
    • yMGV - yeast Microarray Global Viewer

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