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(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
VMR1 Multidrug resistance protein, member of the ATP-binding cassette (ABC) family 
Entry:YHL035c
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (50.3 %) ;  |  Homologs in   Hemiascomycota (83.7 %);  Basidiomycota (31 %);  Fungi (83.7 %);  Eukaryota (83.7 %);  Plants (28.9 %);  Mammalia (31.9 %);  Human (30.9 %);  Bacteria (25.5 %);  All except yeast (83.7 %)

  • similarity to YKR103w, YLL048c, Ycf1p, Yor1p and human multidrug resistance protein
  • member of the ATP-binding transport (ABC transporter family)
Functional Classification:
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transport facilities
    ....ABC transporters | 28 Entries | Evi
  • PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
    ..nucleotide/nucleoside/nucleobase binding
    ....ATP binding | 191 Entries | Evi | PUBMED
TC Class:
  • The Driven Transporters
    ..The P-P Bond Hydrolysis - Driven Transporters
    ....The ATP Binding Cassette (ABC) Superfamily
    ......The Conjugate Transporter-1 (CT1) Subfamily | 6 Entries | Evi | PUBMED
InterPro:
Localization:  VMR1 localization details
  • integral membrane / endomembranes (not assigned to a specific membrane)
  • mitochondria
Phenotypes:  Disruption: VMR1 details
  • viable
___
  • disruptants show very slow growth | PUBMED
___
Click for larger Map
Physical Features
Coordinates:32754 - 27976 (C)
Length:4779 nt
Contig:chrVIII
Exon Coordinates:32754 - 27976
GC Content:35.8 %
Protein Length:1592 aa
Isoelectric Point:8.73
Molecular Weight:180928 Da
Transmembrane Domains:Begin - End / Length (aa)
28 - 47 / 20
170 - 189 / 20
193 - 212 / 20
336 - 358 / 23
378 - 400 / 23
465 - 487 / 23
491 - 513 / 23
569 - 591 / 23
980 - 1002 / 23
1036 - 1058 / 23
1114 - 1136 / 23
1141 - 1163 / 23
1224 - 1246 / 23
1253 - 1275 / 23

14 TM- Domains
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: U11583
PIR: S48933
UniProtKB: P38735
NCBI: NP_011828
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

  • To submit new information about this entry, please write to

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