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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
GUT1 Glycerol kinase 
Entry:YHL032c
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (16.5 %) ;  |  Homologs in   Hemiascomycota (95.3 %);  Basidiomycota (33.2 %);  Fungi (95.3 %);  Eukaryota (95.3 %);  Plants (31.4 %);  Mammalia (34.7 %);  Human (33.3 %);  Bacteria (33.8 %);  All except yeast (95.3 %)

  • similarity to human glycerol kinase and other glycerol kinases
  • belongs to a family that includes fucokinase, gluconokinase, glycerokinase and xylulokinase
Functional Classification:
EC Number:
  • 2.7.1.30: Transferases
    ..Transferring Phosphorus-Containing Groups
    ....Phosphotransferases with an Alcohol Group as Acceptor
    ......glycerol kinase | 1 Entry | Evi | PUBMED
Pathway:
  • rate-limiting step in glycerol utilization
InterPro:
Localization:  GUT1 localization details
  • cytoplasm
  • mitochondria
  • punctate composite
 TargetP: Mitochondrion  (RC = 1)
 Mitop2:  Mitochondrial probability - 97  %
Remarks:
  • glycerol utilization
  • human GK gene involved in glycerol kinase deficiency
  • derepression is defective in adr1 mutant
    Phenotypes:  Disruption: GUT1 details
    • viable
    Click for larger Map
    Physical Features
    Coordinates:38506 - 36377 (C)
    Length:2130 nt
    Contig:chrVIII
    Exon Coordinates:38506 - 36377
    GC Content:47 %
    Protein Length:709 aa
    Isoelectric Point:8.27
    Molecular Weight:79824.7 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: U11583
    PIR: S33907
    UniProtKB: P32190
    NCBI: NP_011831
    Additional Links:
    CYGD Tables:
  • The Yeast homologues of human disease-associated genes
  • LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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