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MPact protein interaction

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About CYGD

MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
RPS23A 40S small subunit ribosomal protein S23.e 
Alias:G6178; (RPS28A)
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Paralogs (100 %) ;  |  Homologs in   Hemiascomycota (100 %);  Basidiomycota (83.4 %);  Fungi (100 %);  Eukaryota (100 %);  Plants (76.6 %);  Mammalia (76.6 %);  Human (76.6 %);  Bacteria (31.7 %);  All except yeast (100 %)

  • identical to rpS23B
  • strong similarity to mammalian ribosomal S23 proteins
  • strong similarity to bacterial ribosomal S12 proteins
Functional Classification:
Localization:  RPS23A localization details
  • cytoplasm
  • RPS23A and RPS23B code for identical proteins
    Phenotypes:  Disruption: RPS23A details
    • viable
    • some mutants increase translational fidelity and increase antibiotic resistance
    • mutants affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin
    • mutations of K62 to N, T or Q increase translational accurancy in vitro
    • Sensitivity to antibiotics
      ..aminoglycoside antibiotics
      ....other or general aminoglycoside antibiotics
      ......other or general aminoglycoside antibiotics resistance | 1 Entry
    Click for larger Map
    Physical Features
    Coordinates:726978 - 727735 (W)
    Length:758 nt
    Exon Coordinates:726978 - 727042 | Evi
    727363 - 727735 | Evi
    GC Content:42.7 %
    Protein Length:145 aa
    Isoelectric Point:10.73
    Molecular Weight:16037.9 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z72903
    EMBL: M96570
    PIR: A46703
    UniProtKB: P32827
    NCBI: NP_011633
    NCBI: NP_015457
    NCBI: XP_448986
    Additional Links:
    CYGD Tables:
  • S. cerevisiae Cytoplasmic Ribosomal Nomenclature
  • LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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