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(chrI - chrXVI,chrMito,2-micron)

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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
VHT1 Biotin (vitamin H) permease 
Entry:YGR065c
Alias:G4539
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (38.8 %) ;  |  Homologs in   Hemiascomycota (97.8 %);  Basidiomycota (25.3 %);  Fungi (97.8 %);  Eukaryota (97.8 %);  Plants (17.9 %);  Mammalia (16 %);  Human (15.2 %);  Bacteria (18.7 %);  All except yeast (97.8 %)

  • strong similarity to Seo1p, similarity to Fen2p, YIL166c, YGR260w and YLR004c
  • similarity to P.putida phthalate transporter
Functional Classification:
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transport facilities | 196 Entries | Evi
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transported compounds (substrates)
    ....ion transport
    ......cation transport (H+, Na+, K+, Ca2+ , NH4+, etc.) | 122 Entries | Evi
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transported compounds (substrates)
    ....vitamine/cofactor transport | 14 Entries | Evi | PUBMED
TC Class:
  • The Uni/Sym/Antiporters
    ..The Uni/Sym/Antiporters
    ....The Major Facilitator (MFS) Superfamily
    ......The Anion: Cation Symporter (ACS) Subfamily | 9 Entries | Evi | PUBMED
InterPro:
Localization:  VHT1 localization details
  • bud
  • cell periphery
Phenotypes:  Disruption: VHT1 details
  • lethal
  • viable
___
  • mutant strain has strongly reduced biotin uptake and reduced levels of protein biotinylation | PUBMED
Click for larger Map
Physical Features
Coordinates:619862 - 618081 (C)
Length:1782 nt
Contig:chrVII
Exon Coordinates:619862 - 618081
GC Content:39 %
Protein Length:593 aa
Isoelectric Point:9.02
Molecular Weight:69083 Da
Transmembrane Domains:Begin - End / Length (aa)
121 - 138 / 18
166 - 188 / 23
225 - 247 / 23
293 - 315 / 23
367 - 389 / 23
404 - 426 / 23
433 - 451 / 19
461 - 480 / 20
493 - 515 / 23
525 - 547 / 23

10 TM- Domains
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z72850
PIR: S64360
UniProtKB: P53241
NCBI: NP_011579
Additional Links:
CYGD Tables:
  • Classification of the Major Facilitator Superfamily
  • LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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