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Chromosome
(chrI - chrXVI,chrMito,2-micron)

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  I  II  III  IV  V  VI  VII
  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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WUBLAST DNA/Protein

About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
CUP2 Copper-dependent transcription factor 
Entry:YGL166w
Alias:ACE1; G1810
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (12.6 %) ;  |  Homologs in   Hemiascomycota (74.7 %);  Basidiomycota (15.3 %);  Fungi (74.7 %);  Eukaryota (74.7 %);  Plants (18.9 %);  Mammalia (22.3 %);  Human (22.1 %);  Bacteria (20.9 %);  All except yeast (74.7 %)
  • similarity to Amt1p, YPR008w and Y.lipolytica CRF1 protein
Functional Classification:
  • INTERACTION WITH THE ENVIRONMENT
    ..homeostasis
    ....homeostasis of cations
    ......homeostasis of metal ions (Na, K, Ca etc.) | 98 Entries | Evi
  • CELL RESCUE, DEFENSE AND VIRULENCE
    ..disease, virulence and defense
    ....resistance proteins
    ......chemical agent resistance
    ........inorganic chemical agent resistance (e.g. heavy metals) | 7 Entries | Evi | PUBMED
  • TRANSCRIPTION
    ..RNA synthesis
    ....mRNA synthesis
    ......transcriptional control | 495 Entries | Evi
  • TRANSCRIPTION
    ..RNA synthesis
    ....mRNA synthesis
    ......general transcription activities
    ........transcription initiation | 46 Entries | Evi | PUBMED
InterPro:
Localization:  CUP2 localization details
  • cytoplasm
  • nucleus
Remarks:
    • contains a copper-fist domain
    • binds DNA only in presence of copper or silver
    • conformation is altered upon binding copper ion
Phenotypes:  Disruption: CUP2 details
  • viable
___
  • ace1 mutants do not have copper induction of Sod1p
Click for larger Map
Physical Features
Coordinates:191135 - 191812 (W)
Length:678 nt
Contig:chrVII
Exon Coordinates:191135 - 191812
GC Content:47.3 %
Protein Length:225 aa
Isoelectric Point:7.97
Molecular Weight:24425.5 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z72688
EMBL: Z48618
EMBL: M22580
EMBL: M24390
EMBL: X85757
PIR: A31926
UniProtKB: P15315
NCBI: NP_011349
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
    • To submit new information about this entry, please write to

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