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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
VPS73 Protein involved in vacuolar protein sorting 
Entry:YGL104c
Alias:G3090
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (46.3 %) ;  |  Homologs in   Hemiascomycota (88.1 %);  Basidiomycota (27 %);  Fungi (88.1 %);  Eukaryota (88.1 %);  Plants (26.7 %);  Mammalia (28 %);  Human (27.6 %);  Bacteria (26.9 %);  All except yeast (88.1 %)

  • strong similarity to YBR241c, similarity to mammalian glucose transport proteins
Functional Classification:
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transport routes
    ....vacuolar/lysosomal transport | 154 Entries | Evi | PUBMED
  • PROTEIN FATE (folding, modification, destination)
    ..protein targeting, sorting and translocation | 280 Entries | Evi | PUBMED
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transported compounds (substrates)
    ....C-compound and carbohydrate transport | 63 Entries | Evi
TC Class:
  • The Uni/Sym/Antiporters
    ..The Uni/Sym/Antiporters
    ....The Major Facilitator (MFS) Superfamily
    ......The Sugar Porter (SP) Subfamily | 32 Entries | Evi | PUBMED
InterPro:
Localization:  VPS73 localization details
  • mitochondria
 TargetP: Mitochondrion  (RC = 3)
Remarks:
    Phenotypes:  Disruption: VPS73 details
    • viable
    Click for larger Map
    Physical Features
    Coordinates:310176 - 308716 (C)
    Length:1461 nt
    Contig:chrVII
    Exon Coordinates:310176 - 308716
    GC Content:39.6 %
    Protein Length:486 aa
    Isoelectric Point:9.29
    Molecular Weight:54331.9 Da
    Transmembrane Domains:Begin - End / Length (aa)
    27 - 44 / 18
    91 - 113 / 23
    145 - 167 / 23
    209 - 228 / 20
    306 - 324 / 19
    339 - 361 / 23
    368 - 385 / 18
    395 - 417 / 23
    429 - 451 / 23
    455 - 476 / 22

    10 TM- Domains
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: X97644
    EMBL: Z72626
    PIR: S64111
    UniProtKB: P53142
    NCBI: NP_011411
    Additional Links:
    CYGD Tables:
  • Classification of the Major Facilitator Superfamily
  • LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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