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Chromosome
(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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WUBLAST DNA/Protein

About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
PIB2 Phosphatidylinositol 3-phosphate binding 
Entry:YGL023c
Alias:G3679
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Overlapping Feature:
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (12.8 %) ;  |  Homologs in   Hemiascomycota (92 %);  Basidiomycota (14.3 %);  Fungi (92 %);  Eukaryota (92 %);  Plants (12.6 %);  Mammalia (18.2 %);  Human (18.2 %);  Bacteria (16.6 %);  All except yeast (92 %)
  • weak similarity to Vsp27p
Functional Classification:
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transport routes
    ....vacuolar/lysosomal transport | 154 Entries | Evi | PUBMED
  • PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
    ..lipid binding | 17 Entries | Evi | PUBMED
InterPro:
Localization:  PIB2 localization details
  • cytoplasm
  • mitochondria
  • vacuole
    ..vacuolar membrane
Remarks:
  • gene name synonym MTO1 (including all MTO1 concerning annotation) was incorrect; gene name MTO1 was probably used because of a misprint in paper 9774408 there they describe ORF YGL23c instead of ORF YGL236c | PUBMED
  • contains the zinc-binding RING finger motif related FYVE finger motif at position 449-525, shown to bind phosphatidylinositol-3-P (PtdIns(3)P) in related the proteins Vps27p, Pep7p, Fab1p and Pib1p | PUBMED
Phenotypes:  Disruption: PIB2 details
  • viable
Click for larger Map
Physical Features
Coordinates:452109 - 450202 (C)
Length:1908 nt
Contig:chrVII
Exon Coordinates:452109 - 450202
GC Content:46.6 %
Protein Length:635 aa
Isoelectric Point:7.65
Molecular Weight:70616.8 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z72545
PIR: S64025
UniProtKB: P53191
NCBI: NP_011492
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
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