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MPact protein interaction

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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
PTC2 Protein serine/threonine phosphatase of the PP2C family 
Entry:YER089c
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (61.5 %) ;  |  Homologs in   Hemiascomycota (97 %);  Basidiomycota (36.8 %);  Fungi (97 %);  Eukaryota (97 %);  Plants (30.6 %);  Mammalia (23.7 %);  Human (22.2 %);  Bacteria (15.9 %);  All except yeast (97 %)

  • strong similarity to Ptc3p, S.pombe protein phosphatase 2C and other phosphoprotein phosphatases
Functional Classification:
  • CELL RESCUE, DEFENSE AND VIRULENCE
    ..stress response
    ....unfolded protein response (e.g. ER quality control) | 69 Entries | Evi | PUBMED
  • CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM
    ..cellular signalling
    ....enzyme mediated signal transduction
    ......protein kinase
    ........MAPKKK cascade | 27 Entries | Evi | PUBMED
  • INTERACTION WITH THE ENVIRONMENT
    ..cellular sensing and response to external stimulus
    ....chemoperception and response
    ......osmosensing and response | 35 Entries | Evi | PUBMED
  • PROTEIN FATE (folding, modification, destination)
    ..protein modification
    ....modification by phosphorylation, dephosphorylation, autophosphorylation | 186 Entries | Evi | PUBMED
  • CELL CYCLE AND DNA PROCESSING
    ..cell cycle
    ....mitotic cell cycle and cell cycle control
    ......mitotic cell cycle
    ........G1/S transition of mitotic cell cycle | 37 Entries | Evi | PUBMED
  • CELL CYCLE AND DNA PROCESSING
    ..cell cycle
    ....mitotic cell cycle and cell cycle control
    ......cell cycle arrest | 21 Entries | Evi | PUBMED
  • REGULATION OF METABOLISM AND PROTEIN FUNCTION
    ..regulation of protein activity
    ....enzymatic activity regulation / enzyme regulator
    ......enzyme inhibitor
    ........kinase inhibitior | 14 Entries | Evi | PUBMED
EC Number:
  • 3.1.3.16: Hydrolases
    ..Acting on Ester Bonds
    ....Phosphoric Monoester Hydrolases
    ......phosphoprotein phosphatase | 25 Entries
InterPro:
Localization:  PTC2 localization details
  • cytoplasm
  • nucleus
Remarks:
    • protein phosphatase type 2C
Phenotypes:  Disruption: PTC2 details
  • viable
Click for larger Map
Physical Features
Coordinates:337336 - 335942 (C)
Length:1395 nt
Contig:chrV
Exon Coordinates:337336 - 335942
GC Content:48.6 %
Protein Length:464 aa
Isoelectric Point:4.84
Molecular Weight:50388.3 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: U18839
EMBL: U72498
PIR: S50592
UniProtKB: P39966
NCBI: NP_011013
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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