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(chrI - chrXVI,chrMito,2-micron)

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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
WBP1 Oligosaccharyl transferase beta subunit precursor 
Entry:YEL002c
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (16.5 %) ;  |  Homologs in   Hemiascomycota (94.2 %);  Basidiomycota (26.8 %);  Fungi (94.2 %);  Eukaryota (94.2 %);  Plants (28.4 %);  Mammalia (25.4 %);  Human (24.8 %);  Bacteria (20.4 %);  All except yeast (94.2 %)

  • similarity to oligosaccharyltransferases from other species
Functional Classification:
  • METABOLISM
    ..C-compound and carbohydrate metabolism
    ....polysaccharide metabolism
    ......peptidoglycan metabolism
    ........peptidoglycan anabolism | 17 Entries | Evi | PUBMED
  • PROTEIN FATE (folding, modification, destination)
    ..protein modification
    ....modification with sugar residues (e.g. glycosylation, deglycosylation)
    ......N-directed glycosylation, deglycosylation | 43 Entries | Evi | PUBMED
EC Number:
  • 2.4.1.119: Transferases
    ..Glycosyltransferases
    ....Hexosyltransferases
    ......dolichyl-diphosphooligosaccharide?protein glycotransferase | 9 Entries | Evi | PUBMED
Pathway:
  • glycosylation
InterPro:
Localization:  WBP1 localization details
  • ER
 TargetP: Secretory pathway  (RC = 1)
Remarks:
    • has dilysine KKXX C-terminal motif for retrieval from Golgi to the ER
Phenotypes:  Disruption: WBP1 details
  • lethal
___
  • wbp1-2 mutant has underglycosylated carboxypeptidase Y (CPY or Prc1p)
Suppression:
  • can be suppressed by overexpression of Swp1p
Click for larger Map
Physical Features
Coordinates:150013 - 148721 (C)
Length:1293 nt
Contig:chrV
Exon Coordinates:150013 - 148721
GC Content:38.5 %
Protein Length:430 aa
Isoelectric Point:5.62
Molecular Weight:49391.9 Da
Mature Protein:21-430
Transmembrane Domains:Begin - End / Length (aa)
393 - 415 / 23

1 TM- Domain
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: X61388
EMBL: U18530
PIR: S20187
UniProtKB: P33767
NCBI: NP_010914
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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