| Entry: | YDR436w |
| Alias: | D9461.22 |
| Classification: | known protein | 5422 Entries | Evi
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PUBMED
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| Feature Type: | CDS |
| Features |
 |
Blast-Simap
DNA VIEW
PROTEIN VIEW
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| Similarity: |
belongs to the PP-Z subfamily of the PPP family of phosphatasesstrong similarity to Ppz1p and other phosphoprotein phosphatases |
| Functional Classification: | - INTERACTION WITH THE ENVIRONMENT
..homeostasis ....homeostasis of cations ......homeostasis of metal ions (Na, K, Ca etc.)
| 98 Entries | Evi
|
PUBMED
- CELL RESCUE, DEFENSE AND VIRULENCE
..stress response
| 450 Entries | Evi
- CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM
..cellular signalling ....enzyme mediated signal transduction ......protein kinase
| 57 Entries | Evi
|
PUBMED
- PROTEIN FATE (folding, modification, destination)
..protein modification ....modification by phosphorylation, dephosphorylation, autophosphorylation
| 186 Entries | Evi
|
PUBMED
|
| EC Number: | - 3.1.3.16: Hydrolases
..Acting on Ester Bonds ....Phosphoric Monoester Hydrolases ......phosphoprotein phosphatase
| 25 Entries
|
|
InterPro:
| |
| Localization: | PPZ2 localization details |
| Phenotypes: | Disruption: PPZ2 details___
mutants are osmosensitiveppz1 ppz2 double mutants have temperature-sensitive osmoremedial cell lysis defectmutations affect pseudohyphal growthmutants are affected in pseudohyphal growthnull mutant has little affect on salt toleranceppz1 ppz2 double null mutant has more salt tolerance than ppz1 aloneppz1 ppz2 double null mutant has same Li+ influx rate but much faster efflux rate than wild-typeppz1 ppz2 double null mutant has much higher level of Ena1p which is responsible for Li+ effluxppz1 ppz2 double null mutant has increased sensitivity to caffeine leading to cell lysis ___
Cell morphology and organelle mutants ..Budding mutants ....Pseudohyphae formation | 31 Entries Cell morphology and organelle mutants ..Cell wall mutants ....Osmotic sensitivity (Osm) | 43 Entries |
| Overexpression: | overproduction suppresses Mpk1 null mutationoverproduction suppresses rho1-104 temperature-sensitive mutation |