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(chrI - chrXVI,chrMito,2-micron)

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  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
SFA1 Long-chain alcohol dehydrogenase 
Entry:YDL168w
Alias:D1473; SFA
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (27.4 %) ;  |  Homologs in   Hemiascomycota (95.9 %);  Basidiomycota (65 %);  Fungi (95.9 %);  Eukaryota (95.9 %);  Plants (60.1 %);  Mammalia (61.1 %);  Human (61.1 %);  Bacteria (63 %);  All except yeast (95.9 %)
  • strong similarity to mammalian ADH CLASS-III
Functional Classification:
EC Number:
  • 1.2.1.1: Oxidoreductases
    ..Acting on the aldehyde or oxo group of donors
    ....With NAD+ or NADP+ as acceptor
    ......deleted, replaced by EC 1.1.1.284 and EC 4.4.1.22 | 1 Entry | Evi | PUBMED
Cofactor:
  • zinc
InterPro:
Localization:  SFA1 localization details
  • cytoplasm
  • mitochondria
Remarks:
  • responsible for yeast resistance to formaldehyde
  • inducible by formaldehyde, ethanol and methyl methanesulfonate
  • TM is predicted false positive
    Phenotypes:  Disruption: SFA1 details
    • viable
    Overexpression:
    • overproduction leads to resistance to formaldehyde
    Click for larger Map
    Physical Features
    Coordinates:159605 - 160765 (W)
    Length:1161 nt
    Contig:chrIV
    Exon Coordinates:159605 - 160765
    GC Content:42.8 %
    Protein Length:386 aa
    Isoelectric Point:6.33
    Molecular Weight:41042.3 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z74216
    EMBL: X68020
    EMBL: Z67750
    PIR: S31140
    UniProtKB: P32771
    NCBI: NP_010113
    Additional Links:
    LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
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