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(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
RDI1 Rho GDP dissociation inhibitor with activity toward Rho1p 
Entry:YDL135c
Alias:D2175
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (12.4 %) ;  |  Homologs in   Hemiascomycota (99 %);  Basidiomycota (37.1 %);  Fungi (99 %);  Eukaryota (99 %);  Plants (32 %);  Mammalia (40.1 %);  Human (37.2 %);  Bacteria (20.1 %);  All except yeast (99 %)
  • strong similarity to mammalian rho GDI
Functional Classification:
  • CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM
    ..cellular signalling
    ....enzyme mediated signal transduction
    ......G-protein mediated signal transduction
    ........small GTPase mediated signal transduction | 58 Entries | Evi | PUBMED
  • CELL TYPE DIFFERENTIATION
    ..fungal/microorganismic cell type differentiation
    ....fungal and other eukaryotic cell type differentiation
    ......budding, cell polarity and filament formation | 313 Entries | Evi
  • CELL FATE
    ..cell growth / morphogenesis
    ....directional cell growth (morphogenesis) | 37 Entries | Evi
  • BIOGENESIS OF CELLULAR COMPONENTS
    ..cytoskeleton/structural proteins
    ....actin cytoskeleton | 96 Entries | Evi | PUBMED
  • REGULATION OF METABOLISM AND PROTEIN FUNCTION
    ..regulation of protein activity
    ....enzymatic activity regulation / enzyme regulator
    ......enzyme inhibitor
    ........GTPase inhibitor (GIP) | 5 Entries | Evi | PUBMED
  • REGULATION OF METABOLISM AND PROTEIN FUNCTION
    ..regulation of protein activity
    ....regulator of G-protein signalling | 15 Entries | Evi
InterPro:
Localization:  RDI1 localization details
  • cytoplasm
  • nucleus
Remarks:
  • Rdi1p produced in E. coli is active on yeast and mammalian rho family proteins
    Phenotypes:  Disruption: RDI1 details
    • viable
    ___
    • null mutant is normal for growth, sporulation, heat shock, mating, and budding
    Overexpression:
    • overexpression inhibits cell growth
    Click for larger Map
    Physical Features
    Coordinates:219288 - 218680 (C)
    Length:609 nt
    Contig:chrIV
    Exon Coordinates:219288 - 218680
    GC Content:36.9 %
    Protein Length:202 aa
    Isoelectric Point:5.77
    Molecular Weight:23138.3 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z74183
    EMBL: D31630
    EMBL: X96876
    PIR: A53646
    UniProtKB: Q12434
    NCBI: NP_010146
    Additional Links:
    LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
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