| Entry: | YDL035c |
| Alias: | D2749 |
| Classification: | known protein | 5422 Entries |
| Feature Type: | CDS |
| Overlapping Feature: | |
| Features |
 |
Blast-Simap
DNA VIEW
PROTEIN VIEW
|
| Similarity: |
weak similarity to Dictyostelium protein tyrosine phosphatasebelongs to the G protein-coupled receptor superfamily, see |
PUBMED
|
| Functional Classification: | - CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM
..transmembrane signal transduction
....non-enzymatic receptor mediated signalling
......G-protein coupled receptor signalling pathway
| 7 Entries | Evi
|
PUBMED
- CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM
..cellular signalling
....enzyme mediated signal transduction
......G-protein mediated signal transduction
| 69 Entries | Evi
|
PUBMED
- CELL TYPE DIFFERENTIATION
..fungal/microorganismic cell type differentiation
....fungal and other eukaryotic cell type differentiation
......budding, cell polarity and filament formation
| 313 Entries | Evi
|
PUBMED
- INTERACTION WITH THE ENVIRONMENT
..cellular sensing and response to external stimulus
....perception of nutrients and nutritional adaptation
| 33 Entries | Evi
|
|
Pathway: | GPR1/GPA2 signalling pathway |
| TC Class: | - Non Transporting Mebrane Proteins
..Signaling
....G-Receptors
......The Seven TMS Receptors Subfamily | 5 Entries |
Evi
|
PUBMED
|
| Localization: | GPR1 localization details |
| Remarks: | predicted to have 7 transmembrane spans |
PUBMED
extremely large loop between 5th and 6th transmembrane region (aa 273-622) and a long C-terminal region (679-961), both are likely to be located intracellular |
PUBMED
asparagine rich domain aa 471-587 |
PUBMED
five potential phosphorylation sites by cAMP dependent protein kinase in the second, third and C-terminal region |
PUBMED
many serine and threonine residues at C-terminal tail as found in mammalian G-protein coupled receptors |
PUBMED
interaction with Gpa2p via third cytosolic loop and C-terminal tail |
PUBMED
the 4C-N domain (aa 679-862) shows inhibitory effect to the interaction between aa 831-961 with Gpa2p |
PUBMED
|
| Phenotypes: | Disruption: GPR1 details |
