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About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
SUL1 Sulfate permease I 
Entry:YBR294w
Alias:SEL3; SFP; YBR2110
Classification:known protein | 5422 Entries
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (63.1 %) ;  |  Homologs in   Hemiascomycota (94.5 %);  Basidiomycota (40.5 %);  Fungi (94.5 %);  Eukaryota (94.5 %);  Plants (19.6 %);  Mammalia (22.1 %);  Human (22 %);  Bacteria (18.8 %);  All except yeast (94.5 %)
  • similarity to human sulfate transporter protein DTD involved in diastrophic dysplasia
  • similarity to sulfate permease family of the major facilitator superfamily (MFS)
Functional Classification:
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transport routes
    ....cellular import | 150 Entries | Evi
  • INTERACTION WITH THE ENVIRONMENT
    ..homeostasis
    ....homeostasis of anions
    ......homeostasis of sulfate | 3 Entries | Evi
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transported compounds (substrates)
    ....ion transport
    ......anion transport
    ........sulfate/sulfite transport | 3 Entries | Evi | PUBMED
TC Class:
  • The Uni/Sym/Antiporters
    ..The Uni/Sym/Antiporters
    ....The Sulfate Permease (SulP) Family
    ......The Sulfate Permease (SulP-1) Subfamily Type 1 | 3 Entries | Evi | PUBMED
InterPro:
Localization:  SUL1 localization details
  • plasma membrane
Remarks:
  • sulfate transporter recognize selenate and chromate
    Phenotypes:  Disruption: SUL1 details
    • viable
    ___
    • sul1 sul2 double null mutants requires greater than 5 mM sulfate for growth | PUBMED
    • restricted growth on sulfate as a sole source of sulfur | PUBMED
    • sul1 mutant is selenate resistant | PUBMED
    ___
    • Auxotrophies, carbon and nitrogen utilization defects
      ..other auxotrophies, carbon and nitrogen utilization defects | 20 Entries
    • Stress response defects
      ..Divalent cations and heavy metals
      ....Divalent cations and heavy metals resistance | 13 Entries
    Click for larger Map
    Physical Features
    Coordinates:789230 - 791809 (W)
    Length:2580 nt
    Contig:chrII
    Exon Coordinates:789230 - 791809
    GC Content:39.9 %
    Protein Length:859 aa
    Isoelectric Point:6.35
    Molecular Weight:95951.3 Da
    Transmembrane Domains:Begin - End / Length (aa)
    118 - 140 / 23
    205 - 227 / 23
    234 - 256 / 23
    290 - 312 / 23
    333 - 355 / 23
    396 - 415 / 20
    428 - 450 / 23
    465 - 487 / 23
    523 - 545 / 23
    9 TM- Domains
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z36163
    EMBL: Z35134
    PIR: S46176
    UniProtKB: P38359
    NCBI: NP_009853
    Additional Links:
    CYGD Pathways:
  • Sulfur amino acid biosynthesis
    • CYGD Tables:
  • The Yeast homologues of human disease-associated genes
  • Classification of the Major Facilitator Superfamily
    • LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
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