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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
POP7 Nuclear RNase P subunit 
Entry:YBR167c
Alias:RPP2; YBR1219
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Overlapping Feature:
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (17.2 %) ;  |  Homologs in   Hemiascomycota (84.3 %);  Basidiomycota (7.1 %);  Fungi (84.3 %);  Eukaryota (84.3 %);  Plants (15 %);  Mammalia (21.4 %);  Human (17.8 %);  Bacteria (26 %);  All except yeast (84.3 %)

  • similarity to human protein Rpp20
Functional Classification:
EC Number:
  • 3.1.26.5: Hydrolases
    ..Acting on Ester Bonds
    ....Endoribonucleases Producing 5'-Phosphomonoesters
    ......ribonuclease P | 10 Entries | Evi | PUBMED
Localization:  POP7 localization details
  • nucleus
  • nucleus
    ..nucleolus
Remarks:
  • Ribonuclease P Protein 2
    Phenotypes:  Disruption: POP7 details
    • lethal
    ___
    • rpp2 deletion mutant causes accumulation of unspliced tRNA^s and unprocessed 5^- and 3^-termini | PUBMED
    • rpp2 deletion mutant is defective in processing of the 35S precursor rRNA and 5.8S rRNA | PUBMED
    • depletion leads to pre-tRNA and pre-rRNA processing defects | PUBMED
    • depletion does lead to reduction of endogenous levels of RNase P and RNase MRP RNAs, but not of pre-RNase P | PUBMED
    Click for larger Map
    Physical Features
    Coordinates:571885 - 571463 (C)
    Length:423 nt
    Contig:chrII
    Exon Coordinates:571885 - 571463
    GC Content:36.2 %
    Protein Length:140 aa
    Isoelectric Point:9.34
    Molecular Weight:15814.3 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z36036
    EMBL: AF055991
    PIR: S46038
    UniProtKB: P38291
    NCBI: NP_009726
    Additional Links:
    LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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