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(chrI - chrXVI,chrMito,2-micron)

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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
CNS1 Cyclophilin seven suppressor; component of Hsp90p chaperone machinery 
Entry:YBR155w
Alias:YBR1205
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (14 %) ;  |  Homologs in   Hemiascomycota (92.2 %);  Basidiomycota (31.1 %);  Fungi (92.2 %);  Eukaryota (92.2 %);  Plants (24.4 %);  Mammalia (23.5 %);  Human (23.3 %);  Bacteria (16.4 %);  All except yeast (92.2 %)

  • weak similarity to stress-induced STI1p
Functional Classification:
  • CELL RESCUE, DEFENSE AND VIRULENCE
    ..stress response
    ....unfolded protein response (e.g. ER quality control) | 69 Entries | Evi | PUBMED
  • PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
    ..protein binding | 392 Entries | Evi | PUBMED
InterPro:
Localization:  CNS1 localization details
  • cytoplasm
Remarks:
    • N-terminal half contains three tetratricopeptide repeats (TPR), related to those found in Cpr6p and Cpr7p | PUBMED
Phenotypes:  Disruption: CNS1 details
  • lethal
Overexpression:
  • overexpression of CNS1 restores rapid growth and increases Hsp90 activity in cpr7* cells
Click for larger Map
Physical Features
Coordinates:549765 - 550922 (W)
Length:1158 nt
Contig:chrII
Exon Coordinates:549765 - 550922
GC Content:38.9 %
Protein Length:385 aa
Isoelectric Point:5.69
Molecular Weight:44112.6 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z36024
PIR: S40699
UniProtKB: P33313
NCBI: NP_009713
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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