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Entry information

Protein complex ID:652
Last modified on:2008-08-22

Protein complex name and species

Name:

AP3-BLOC1 complex

Organism:Human

Subunits

Protein descriptionGene nameGene synonymsOrganismUniProt IDEntrez-ID
AP-3 complex subunit beta-1AP3B1ADTB3AHomo sapiensO002038546
AP-3 complex subunit beta-2AP3B2Homo sapiensQ133678120
AP-3 complex subunit delta-1AP3D1PRO0039Homo sapiensO146178943
AP-3 complex subunit mu-1AP3M1Homo sapiensQ9Y2T226985
AP-3 complex subunit mu-2AP3M2Homo sapiensP5367710947
AP-3 complex subunit sigma-1AP3S1CLAPS3Homo sapiensQ925721176
AP-3 complex subunit sigma-2AP3S2Homo sapiensP5978010239
Biogenesis of lysosome-related organelles complex 1 subunit 1BLOC1S1BLOS1, GCN5L1, RT14Homo sapiensP785372647
Biogenesis of lysosome-related organelles complex 1 subunit 2BLOC1S2BLOS2, CEAPHomo sapiensQ6QNY1282991
Biogenesis of lysosome-related organelles complex 1 subunit 3BLOC1S3BLOS3Homo sapiensQ6QNY0388552
Protein cappuccino homologCNOHomo sapiensQ9NUP155330
DysbindinDTNBP1My031Homo sapiensQ96EV884062
Protein Muted homologMUTEDHomo sapiensQ8TDH963915
PallidinPLDNPAHomo sapiensQ9UL4526258
SNARE-associated protein SnapinSNAPINSNAP25BP, SNAPAPHomo sapiensO9529523557

Purification method

  • MI:0019- coimmunoprecipitation

Functional charaterization

FunCatFunCat-EviReference
14 PROTEIN FATE (folding, modification, destination)
14.04 protein targeting, sorting and translocation
exp16837549
42 BIOGENESIS OF CELLULAR COMPONENTS
42.02 eukaryotic plasma membrane
pred16837549

GO characterisation

GOGo description
GO:0006605protein targeting
GO:0015031protein transport
GO:0007009plasma membrane organization and biogenesis

Comment

BLOC-1 interacts physically and functionally with AP-3 to facilitate the trafficking of a known AP-3 cargo.

Reference

PubMed= 16837549

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