Search Results for "SOD1-p.G93A" - 538 interactions found in 130 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
97
317 SOD1-p.G93A increases_quantity of TNF in adult microglia; LPS stimulated
318 SOD1-p.G93A decreases_quantity of IL6 in adult microglia; LPS stimulated
15378658 Amyotrophic lateral sclerosis
98
319 SOD1-p.G93A increases_activity of microglial cell activation in microglia cultures
321 SOD1-p.G93A increases_quantity of TNF in microglia cultures
323 SOD1-p.G93A increases_quantity of IL1B in microglia cultures
324 SOD1-p.G93A increases_expression of CYBB in microglia cultures
325 SOD1-p.G93A increases_expression of NOS2 in microglia cultures
326 SOD1-p.G93A increases_quantity of IGF1 in microglia cultures
329 SOD1-p.G93A increases_quantity of O2- in microglia cultures
331 SOD1-p.G93A interacts (colocalizes) with CD14
19672969 Amyotrophic lateral sclerosis
101
341 SOD1-p.G93A increases_activity of ERN1 in motor neurons
343 SOD1-p.G93A affects_activity of response to endoplasmic reticulum stress in motor neurons
346 SOD1-p.G93A increases_activity of EIF2AK3 in motor neurons
347 SOD1-p.G93A increases_activity of MAP3K5 in motor neurons
353 SOD1-p.G93A increases_quantity of DDIT3 in motor neurons
356 SOD1-p.G93A increases_quantity of HSPA5 in motor neurons
363 SOD1-p.G93A decreases_activity of ER-associated ubiquitin-dependent protein catabolic process in motor neurons
366 SOD1-p.G93A interacts (colocalizes) with DERL1 in motor neurons
398 SOD1-p.G93A increases_activity of motor neuron degeneration in motor neurons
18519638 Amyotrophic lateral sclerosis
106
370 SOD1-p.G93A interacts (colocalizes) with DERL1 in liver
18519638 Amyotrophic lateral sclerosis
107
372 SOD1-p.G93A interacts (colocalizes) with DERL1 in cerebral cortex
18519638 Amyotrophic lateral sclerosis
108
374 SOD1-p.G93A interacts (colocalizes) with DERL1 in cerebellum
18519638 Amyotrophic lateral sclerosis
109
376 SOD1-p.G93A interacts (colocalizes) with DERL1 in medulla
18519638 Amyotrophic lateral sclerosis
111
377 SOD1-p.G93A interacts (colocalizes) with DERL1 in spinal cord
379 SOD1-p.G93A is localized in cytoplasm mainly
381 SOD1-p.G93A is localized in endoplasmic reticulum membrane partly
18519638 Amyotrophic lateral sclerosis
114
387 SOD1-p.G93A NOT affects_quantity of glia
390 SOD1-p.G93A decreases_quantity of motoneuron
18519638 Amyotrophic lateral sclerosis
151
572 SOD1-p.G93A increases_phosphorylation of EIF2AK3 if mutant SOD1 is over-expressed
576 SOD1-p.G93A increases_phosphorylation of EIF2S1 if mutant SOD1 is over-expressed
585 SOD1-p.G93A increases_phosphorylation of MAPK8 if mutant SOD1 is over-expressed
601 SOD1-p.G93A increases_transport of ATF6 into nucleus; if mutant SOD1 is over-expressed
611 SOD1-p.G93A increases_expression of HSPA5 if mutant SOD1 is over-expressed
613 SOD1-p.G93A decreases_expression of BCL2 if mutant SOD1 is over-expressed
614 SOD1-p.G93A increases_expression of BAX if mutant SOD1 is over-expressed
629 SOD1-p.G93A increases_activity of CASP12 if mutant SOD1 is over-expressed
631 SOD1-p.G93A increases_activity of CASP7 if mutant SOD1 is over-expressed
644 SOD1-p.G93A increases_activity of neuron apoptotic process if mutant SOD1 is over-expressed
18233996 Amyotrophic lateral sclerosis
172
691 SOD1-p.G93A increases_activity of response to endoplasmic reticulum stress in motoneurons; from stage P12 up to P26
696 SOD1-p.G93A increases_expression of EIF2A in motoneurons; from stage P32 on
701 SOD1-p.G93A increases_expression of ATF4 in motoneurons; from stage P32 on
702 SOD1-p.G93A increases_expression of GADD45A in motoneurons; from stage P32 on
703 SOD1-p.G93A increases_expression of ATF3 in motoneurons; from stage P32 on
704 SOD1-p.G93A increases_expression of LAPTM5 in motoneurons; from stage P32 on
707 SOD1-p.G93A increases_expression of GRN in motoneurons; from stage P32 on
708 SOD1-p.G93A increases_expression of NRN1 in motoneurons; from stage P32 on
709 SOD1-p.G93A increases_expression of HEXB in motoneurons; from stage P32 on
710 SOD1-p.G93A increases_expression of EIF2AK3 in motoneurons; from stage P32 on
711 SOD1-p.G93A decreases_expression of USP53 in motoneurons; from stage P32 on
712 SOD1-p.G93A decreases_expression of UCHL5 in motoneurons; from stage P32 on
713 SOD1-p.G93A decreases_expression of UBE2Q1 in motoneurons; from stage P32 on
716 SOD1-p.G93A increases_expression of IFIH1 in motoneurons; from stage P32 on
717 SOD1-p.G93A increases_expression of IFITM3 in motoneurons; from stage P32 on
718 SOD1-p.G93A increases_expression of C1QB in motoneurons; from stage P32 on
737 SOD1-p.G93A increases_expression of HSPA5 in motoneurons; from stage P20 to P38
19330001 Amyotrophic lateral sclerosis
177
720 SOD1-p.G93A increases_activity of microglial cell activation between stage P28 and P32
19330001 Amyotrophic lateral sclerosis
196
780 SOD1-p.G93A increases_activity of motor neuron degeneration
784 SOD1-p.G93A increases_activity of response to endoplasmic reticulum stress
786 SOD1-p.G93A increases_quantity of HSPA5
788 SOD1-p.G93A increases_quantity of HSP90B1
789 SOD1-p.G93A increases_quantity of Ubiquitin
793 SOD1-p.G93A increases_expression of DDIT3
794 SOD1-p.G93A increases_expression of BCL2L11
795 SOD1-p.G93A increases_expression of BBC3
13274 SOD1-p.G93A increases_quantity of DDIT3
13275 SOD1-p.G93A increases_quantity of BCL2L11
13276 SOD1-p.G93A increases_quantity of BBC3
18077368 Amyotrophic lateral sclerosis
218
875 SOD1-p.G93A increases_quantity of P4HB
876 SOD1-p.G93A increases_quantity of PDIA3
888 SOD1-p.G93A interacts (colocalizes) with P4HB
890 SOD1-p.G93A increases_quantity of EIF2AK3 at stage p90 and disease end stage p120
891 SOD1-p.G93A increases_quantity of ATF6 at stage p90 and disease end stage p120
892 SOD1-p.G93A increases_quantity of DDIT3 at stage p90 and disease end stage p120
893 SOD1-p.G93A increases_quantity of ERN1 at stage p90 and disease end stage p120
894 SOD1-p.G93A increases_quantity of HSPA5 at disease end stage p120
895 SOD1-p.G93A increases_activity of CASP12 at stage p90 and disease end stage p120
896 SOD1-p.G93A increases_activity of CASP9 at disease end stage p120
897 SOD1-p.G93A increases_activity of CASP3 at disease end stage p120
16847061 Amyotrophic lateral sclerosis
222
13337 AMFR increases_ubiquitination/sumoylation of SOD1-p.G93A
13338 AMFR interacts (colocalizes) with SOD1-p.G93A
13339 AMFR decreases_quantity of SOD1-p.G93A
19661182 Amyotrophic lateral sclerosis
238
986 SOD1-p.G93A increases_quantity of AMFR
13348 SOD1-p.G93A increases_quantity of SOD1 protein aggregates
19661182 Amyotrophic lateral sclerosis
293
1172 SOD1-p.G93A NOT affects_expression of ANG
1175 SOD1-p.G93A decreases_expression of VEGFA
1179 SOD1-p.G93A decreases_expression of KDR
19444281 Amyotrophic lateral sclerosis
310
13452 SOD1-p.G93A increases_activity of p38 MAPK
16581901 Amyotrophic lateral sclerosis
373
1526 SOD1-p.G93A increases_activity of neuron apoptotic process
16000635 Amyotrophic lateral sclerosis
377
1534 SOD1-p.G93A increases_quantity of p38 MAPK in spinal cord
1536 SOD1-p.G93A increases_activity of p38 MAPK in spinal cord
13499 SOD1-p.G93A NOT increases_expression of p38 MAPK in spinal cord
12812752 Amyotrophic lateral sclerosis
379
1555 SOD1-p.G93A increases_quantity of TNF in SOD1(G93A) transgenic mice
17630988 Amyotrophic lateral sclerosis
385
1578 SOD1-p.G93A increases_quantity of TNF in TLR2 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
1582 SOD1-p.G93A decreases_quantity of IL6 in TLR2 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
1583 SOD1-p.G93A NOT increases_expression of TNF in TLR2 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
1586 SOD1-p.G93A increases_quantity of H2O2 in TLR2 or TLR4 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
1592 SOD1-p.G93A increases_activity of response to oxidative stress in TLR2 or TLR4 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
1607 SOD1-p.G93A NOT affects_quantity of IL1B in TLR2 stimulated murine microglial cell line BV-2; if mutSOD1 is overexpressed
19091752 Amyotrophic lateral sclerosis
391
1608 SOD1-p.G93A increases_quantity of TNF in spinal cord motor neurons; especially at stage 90-110 days
1613 SOD1-p.G93A increases_quantity of FASLG in spinal cord motor neurons; as early as 60 days
1621 SOD1-p.G93A increases_activity of motor neuron degeneration in spinal cord motor neurons
1626 SOD1-p.G93A increases_expression of TNF in spinal cord motor neurons
1672 SOD1-p.G93A increases_expression of IL1A in spinal cord; at 110 days of age
1685 SOD1-p.G93A increases_expression of IL1B in spinal cord; at 110 days of age
1688 SOD1-p.G93A increases_expression of IL12B in spinal cord; at 110 days of age
1691 SOD1-p.G93A increases_expression of IL1RN in spinal cord; at 110 days of age
1695 SOD1-p.G93A NOT affects_expression of TGFB1 in spinal cord; at 110 days of age
16510725 Amyotrophic lateral sclerosis
396
1638 SOD1-p.G93A increases_quantity of TNF in astrocytes; at 110 days of age
1648 SOD1-p.G93A increases_quantity of FASLG in astrocytes; as early as 60 days
16510725 Amyotrophic lateral sclerosis
404
1724 SOD1-p.G93A increases_expression of P2RX7 in immortalized microglia
1727 SOD1-p.G93A increases_expression of P2RY6 in immortalized microglia
1728 SOD1-p.G93A decreases_activity of nucleotidase activity in immortalized microglia
1732 SOD1-p.G93A increases_expression of TNF in immortalized microglia
1733 SOD1-p.G93A NOT affects_expression of IL1B in immortalized microglia
1735 SOD1-p.G93A increases_quantity of PTGS2 in immortalized microglia
1767 SOD1-p.G93A increases_activity of microglial cell activation in SOD1G93A transgenic mice
1768 SOD1-p.G93A increases_activity of motor neuron degeneration in SOD1G93A transgenic mice
13503 SOD1-p.G93A NOT increases_expression of P2RX4 in immortalized and primary microglia
13506 SOD1-p.G93A NOT increases_expression of P2RY2 in immortalized and primary microglia
13508 SOD1-p.G93A NOT increases_expression of P2RY12 in immortalized and primary microglia
13509 SOD1-p.G93A increases_quantity of P2RX4 in immortalized and primary microglia
13510 SOD1-p.G93A increases_quantity of P2RX7 in immortalized and primary microglia
13520 SOD1-p.G93A affects_activity of purinergic receptor signaling pathway in immortalized and primary microglia
19734218 Amyotrophic lateral sclerosis
417
1829 SOD1-p.G93A increases_quantity of O2- if SOD1G93A is overexpressed
1832 SOD1-p.G93A affects_activity of RAC1 if SOD1G93A is overexpressed
18219391 Amyotrophic lateral sclerosis
420
1833 SOD1-p.G93A increases_quantity of O2- in brain, spinal cord and liver; if SOD1G93A is overexpressed
18219391 Amyotrophic lateral sclerosis
422
1836 SOD1-p.G93A increases_quantity of O2- if SOD1G93A is overexpressed
1842 SOD1-p.G93A affects_activity of RAC1 if SOD1G93A is overexpressed
18219391 Amyotrophic lateral sclerosis
423
1846 SOD1-p.G93A increases_quantity of O2- if SOD1G93A is overexpressed
18219391 Amyotrophic lateral sclerosis
450
1996 CCS increases_quantity of SOD1-p.G93A in mitochondria; if CCS is overexpressed
17389365 Amyotrophic lateral sclerosis
-->