Search Results for "PARK7" - 272 interactions found in 73 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
8
22 LRRK2 NOT interacts (colocalizes) with PARK7
16352719 Parkinson disease
142
518 PARK7 NOT is localized in aggresome after proteasome inhibition with MG-132
16805805 Parkinson disease
222
13330 AMFR NOT decreases_quantity of PARK7
19661182 Amyotrophic lateral sclerosis
517
2563 PARK7 NOT affects transport of PARK2 into mitochondria; after CCCP treatment
19966284 Parkinson disease
560
2902 PARK7 NOT interacts (colocalizes) with PARK2
2911 PARK2 NOT increases_ubiquitination/sumoylation of PARK7
2915 PARK2 NOT decreases_quantity of PARK7 via ubiquitin-mediated proteasomal degradation
2945 PARK2 NOT increases_transport of PARK7 into aggresome
10117 HDAC6 increases_transport of PARK7 into aggresome
17846173 Parkinson disease
685
3731 PARK7 decreases_activity of neuron death induced by hydrogen peroxide treatment
3733 PARK7 decreases_activity of neuron death induced by LRRK2-G2019S expression
3734 PARK7 decreases_activity of response to oxidative stress
3739 PARK7 decreases_activity of LRRK2-p.G2019S
3740 PARK7 decreases_quantity of H2O2
19769964 Parkinson disease
720
4059 PARK7 affects_activity of LRRK2
19692353 Parkinson disease
851
5065 PARK7 increases_phosphorylation of AKT1 during oxidative stress
5074 PARK7 decreases_activity of neuron death via neuroprotective function of AKT
5077 PARK7 increases_activity of AKT1
20133695 Parkinson disease
852
5071 PARK7 increases_phosphorylation of AKT1 in response to H2O2
20133695 Parkinson disease
854
5084 PARK7 decreases_activity of PTEN
15766664 Cancer
855
5086 PARK7 decreases_activity of neuron death induced by PTEN
5087 PARK7 decreases_activity of PTEN
5096 PARK7 decreases_activity of cell cycle arrest under starvation conditions
5097 PARK7 increases_activity of cell proliferation under starvation conditions
5098 PARK7 increases_activity of Breast cancer
6308 PARK7 increases_phosphorylation of AKT1
6309 PARK7 increases_activity of protein kinase B signaling
15766664 Breast cancer
Parkinson disease
866
5143 PARK7 interacts (colocalizes) with PTEN
17846 PARK7 decreases_activity of PTEN
19885556 Cancer
Parkinson disease
967
5959 PARK7 increases_activity of HRAS
5979 PARK7 increases_activity of MYC
5980 PARK7 affects_activity of Ras protein signal transduction
9070310 Parkinson disease
970
5974 PARK7 interacts (colocalizes) with MYC
5975 PARK7 is localized in cytoplasm
5976 PARK7 is localized in nucleus mainly during S phase of the cell cycle
5978 PARK7 NOT interacts (colocalizes) with HRAS
9070310 Parkinson disease
972
5990 PARK7 increases_activity of Breast cancer
11705844 Breast cancer
973
5991 PARK7 increases_activity of Lung cancer
14583493 Lung cancer
974
5993 PARK7 increases_expression of TOMM20
6004 PARK7 increases_expression of RRN3
6006 PARK7 increases_expression of TMED2
6007 PARK7 increases_expression of LAMP1
6008 PARK7 increases_expression of ABCC3
6009 PARK7 increases_expression of CLNS1A
6010 PARK7 increases_expression of PSIP1
6011 PARK7 increases_expression of LEPR
6012 PARK7 increases_expression of RAB14
6013 PARK7 increases_expression of PIGB
6014 PARK7 increases_expression of NQO1
6015 PARK7 increases_expression of PLA2G16
6016 PARK7 increases_expression of NOG
6017 PARK7 decreases_expression of GREM1
6018 PARK7 decreases_expression of CALR
6019 PARK7 decreases_expression of CTGF
17015834 Parkinson disease
979
6044 PARK7 increases_expression of NQO1 via transcription factor Nrf2
6045 PARK7 increases_quantity of NFE2L2
6054 PARK7 decreases_ubiquitination/sumoylation of NFE2L2
6062 PARK7 increases_quantity of NFE2L2 by preventing its association with Keap1
6065 PARK7 NOT interacts (colocalizes) with NFE2L2
6066 PARK7 NOT interacts (colocalizes) with KEAP1
6067 PARK7 NOT interacts (colocalizes) with CUL3
17015834 Parkinson disease
981
6088 PARK7 NOT affects_quantity of NFE2L2 in nucleus; after tBHQ-treatment
6094 PARK7 decreases_activity of neuron death induced by oxidative stress
20377612 Parkinson disease
982
6096 PARK7 NOT affects_expression of NFE2L2
6097 PARK7 NOT affects_expression of KEAP1
6098 PARK7 NOT affects_expression of CUL3
20377612 Parkinson disease
986
6109 Paraquat increases_transport of PARK7 into mitochondrial outer membrane
6110 response to oxidative stress increases_transport of PARK7 into mitochondrial outer membrane
6111 PARK7 is localized in mitochondrial outer membrane after Paraquat treatment or under oxidative stress conditions
6121 PARK7 decreases_activity of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
6122 PARK7 decreases_activity of neuron death after MPP+ treatment
10456 response to oxidative stress increases_quantity of PARK7 in mitochondria
15181200 Parkinson disease
987
6141 PARK7 decreases_quantity of H2O2 through oxidation of Cys-106
17766438 Parkinson disease
1,003
6256 PARK7 NOT is localized in alpha-synuclein inclusion body
6259 PARK7 affects_quantity of tau protein deposits
14705119 Parkinson disease
Tauopathy
1,005
6266 PARK7 decreases_activity of neuron death induced by oxidative stress
6267 PARK7 decreases_activity of response to oxidative stress
6268 PARK7 decreases_quantity of H2O2
6269 PARK7 decreases_activity of 6-OHDA
6272 PARK7 NOT decreases_activity of Lactacystin
6277 PARK7 increases_quantity of Glutathione
6278 PARK7 increases_activity of GCLC under oxidative stress conditions
6279 PARK7 NOT increases_activity of GSS under oxidative stress conditions
6280 PARK7 increases_expression of GCLC after oxidative stress
6281 PARK7 NOT increases_expression of GSS after oxidative stress
6282 PARK7 decreases_quantity of Reactive oxygen species after oxidative stress
6288 PARK7 decreases_activity of protein oxidation after oxidative stress
6290 PARK7 decreases_quantity of alpha-synuclein inclusion body induced by A35T-SNCA mutant
6292 PARK7 decreases_activity of neuron apoptotic process induced by aggregation of A35T-SNCA mutant
6294 PARK7 increases_quantity of HSP70
6295 PARK7 increases_expression of HSP70
6296 PARK7 decreases_quantity of alpha-synuclein inclusion body by increasing HSP70, thus inhibiting SNCA aggregation
8340 PARK7 affects_activity of Parkinson disease
16227205 Parkinson disease
1,006
6273 PARK7 decreases_activity of neuron death induced by oxidative stress
6275 PARK7 decreases_activity of response to oxidative stress induced by H2O2 or 6-OHDA
16227205 Parkinson disease
1,010
6298 PARK7 interacts (colocalizes) with PIAS2
6299 PARK7 is localized in nucleus
6302 PARK7 increases_activity of AR by impairing the binding of PIASx alpha to the receptor
11477070 Parkinson disease
1,011
6303 PARK7 increases_expression of SOD3
16115732 Parkinson disease
Tauopathy
1,012
6307 PARK7 increases_expression of SOD2
6310 PARK7 increases_expression of GPX1
6311 PARK7 increases_expression of GCLC
6312 PARK7 increases_expression of CAT
18689799 Parkinson disease
1,014
6319 PARK7 increases_quantity of SOD2
18689799 Parkinson disease
1,016
6335 PARK7 increases_activity of PPARGC1A
6338 PARK7 decreases_ubiquitination/sumoylation of SFPQ
6339 PARK7 decreases_quantity of PGC1alpha-PSF complex
6346 PARK7 NOT interacts (colocalizes) with PPARGC1A
18689799 Parkinson disease
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