Search Results for IL6 - 321 interactions found in 142 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
97
318 SOD1-p.G93A decreases_quantity of IL6 in adult microglia; LPS stimulated
15378658 Amyotrophic lateral sclerosis
385
1582 SOD1-p.G93A decreases_quantity of IL6 in TLR2 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
19091752 Amyotrophic lateral sclerosis
682
3716 Status epilepticus increases_expression of IL6 in pilocarpine model
19055492 Status epilepticus
904
5384 high-fat diet increases_expression of IL6 in liver
5388 SIRT1 NOT affects_expression of IL6 in liver; in response to high-fat diet, if SIRT1 is overexpressed
18599449 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
952
5848 IL6 increases_activity of vascular inflammation in brain
5859 Diabetes mellitus, type II increases_quantity of IL6 in blood vessels
20385830 Alzheimer disease
1,086
6939 Lipopolysaccharide increases_expression of IL6
6940 PARK7 affects_expression of IL6 induced by LPS
19276172 Parkinson disease
1,092
7326 TLR4 increases_expression of IL6
45978 adipose tissue macrophage increases_quantity of IL6 in adipose tissue
18053812 Diabetes mellitus, type II
Obesity
Insulin resistance
1,102
7023 Alzheimer disease increases_quantity of IL6 in PBMCs from AD patients compared to PBMCs in healthy controls
20462385 Alzheimer disease
1,103
7038 F2 increases_expression of IL6 via activation of microglia in the substantia nigra
7143 SP600125 NOT decreases_expression of IL6
7145 SB203580 NOT decreases_expression of IL6
20025058 Parkinson disease
1,105
7017 microglial cell activation increases_quantity of IL6
20025058 Parkinson disease
1,108
7109 convulsive seizures increases_expression of IL6
1709015 Epilepsy
1,121
7207 Parkinson disease increases_quantity of IL6 in blood serum
18582534 Parkinson disease
1,122
7212 Parkinson disease increases_quantity of IL6 in striatum but not in cerebral cortex
7700568 Parkinson disease
1,133
7368 convulsive seizures increases_expression of IL6
19845729 Epilepsy, temporal lobe
1,150
7507 MAP3K5 increases_quantity of IL6 after induction with LPS
7513 TLR4 increases_quantity of IL6 after induction with LPS and in the presence of ASK1
15864310 Parkinson disease
1,158
7596 MAPK8 affects_expression of IL6 in liver
7597 Jnk1(+/-)Jnk2(-/-) mouse decreases_expression of IL6 in liver
16818881 Diabetes mellitus, type II
Insulin resistance
1,162
7650 high-fat diet increases_expression of IL6
7690 IKBKB increases_expression of IL6 in LIKK mice
7713 IL6 affects_expression of SOCS1 in muscle; in LIKK mice
7716 Sodium salicylate decreases_expression of IL6 in liver
7725 NFKBIA affects_expression of IL6 in LISR mice
13324 IL6 affects_expression of SOCS2 in muscle; in LIKK mice
13327 IL6 affects_expression of SOCS3 in muscle; in LIKK mice
13331 IL6 affects_expression of STAT3 in muscle; in LIKK mice
15685173 Diabetes mellitus, type II
Insulin resistance
1,170
7730 Schizophrenia increases_expression of IL6
20510460 Schizophrenia
1,177
7776 Schizophrenia increases_expression of IL6
18005941 Schizophrenia
1,185
19317 Risperidone NOT affects_expression of IL6
19318 Haloperidol NOT affects_expression of IL6
19139851 Schizophrenia
1,189
7926 IL6 decreases_activity of insulin receptor signaling pathway in skeletal muscle
7927 IL6 decreases_activity of Phosphatidylinositol 3-kinase in skeletal muscle
7928 IL6 increases_phosphorylation of STAT3 in skeletal muscle; at Tyr residues of STAT3
7929 IL6 increases_activity of Insulin resistance in liver
15047622 Diabetes mellitus, type II
Insulin resistance
1,202
8026 high-fat diet increases_expression of IL6 in liver; in Ikbkb F/F mice
15685170 Diabetes mellitus, type II
Insulin resistance
1,203
8071 CCR2 NOT affects_expression of IL6 in adipose tissue
8073 CCR2 NOT affects_quantity of IL6 in blood
16341265 Diabetes mellitus, type II
Obesity
Insulin resistance
1,204
8102 SNCA-p.A53T increases_expression of IL6 in the brainstem but not in the cerebral cortex of A53T mice
20409326 Parkinson disease
1,207
8095 recruited adipose tissue macrophage affects_expression of IL6
17192460 Diabetes mellitus, type II
Insulin resistance
1,211
8125 SNCA increases_quantity of IL6 in astrocytes
8126 SNCA-p.A30P increases_quantity of IL6 in astrocytes; more efficiently than WT-alpha-synuclein
8127 SNCA-p.E46K increases_quantity of IL6 in astrocytes; more efficiently than WT-alpha-synuclein
8128 SNCA-p.A53T increases_quantity of IL6 in astrocytes; more efficiently than WT-alpha-synuclein
8148 MAPK cascade increases_quantity of IL6 after addition of SNCA
8150 stress-activated MAPK cascade increases_quantity of IL6 after addition of SNCA
17012252 Parkinson disease
1,215
8186 microglial cell activation increases_quantity of IL6
17537546 Parkinson disease
1,217
8201 Estradiol increases_quantity of IL6 in blood; after 3 months of high-fat diet
8204 Estradiol increases_expression of IL6 in liver, in visceral adipose tissue; after 1 month of high-fat feeding
19164473 Diabetes mellitus, type II
Insulin resistance
1,218
8192 SNCA increases_expression of IL6 via microglial cell activation
17537546 Parkinson disease
1,232
8372 C3AR1 affects_expression of IL6
8407 high-fat diet increases_quantity of IL6
8408 C3AR1 NOT affects_quantity of IL6 after high-fat diet
19581423 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
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