Search Results for "AKT1" - 425 interactions found in 180 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
72
227 SEMA3A decreases_phosphorylation of AKT1
16495486 Amyotrophic lateral sclerosis
113
385 Insulin increases_activity of AKT1 by phosphorylation
395 Insulin affects_phosphorylation of AKT1 at Thr308 and Ser473
396 Wortmannin decreases_phosphorylation of AKT1 at Thr308 and Ser473
8978681 Alzheimer disease
115
388 Schizophrenia decreases_expression of AKT1 in prefrontal cortex; in Irish population
17825267 Schizophrenia
116
389 Insulin increases_activity of AKT1
391 IGF1 increases_activity of AKT1
393 Insulin affects_phosphorylation of AKT1 at Thr308 and Ser473
394 IGF1 affects_phosphorylation of AKT1 at Thr308 and Ser473
397 Wortmannin decreases_phosphorylation of AKT1 at Thr308 and Ser473
401 MAPKAPK2 increases_phosphorylation of AKT1 at Ser473
404 MAPKAPK2 increases_activity of AKT1 by phosphorylation at Ser473
8978681 Alzheimer disease
122
909 PSEN1 affects_activity of AKT1
11527574 Alzheimer disease
275
1117 ANG increases_activity of AKT1
19109488 Amyotrophic lateral sclerosis
278
1129 ANG increases_activity of AKT1
1131 ANG-p.K40I NOT increases_activity of AKT1
19109488 Amyotrophic lateral sclerosis
368
1511 ob/ob mouse affects_activity of AKT1
19363290 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
397
1705 NIRKO mouse decreases_phosphorylation of AKT1 in brain
14981233 Alzheimer disease
418
1890 AKT1 interacts (colocalizes) with PDPK1
1943 AKT1 is localized in brain
1954 Amyloid beta peptide decreases_activity of AKT1
1955 Amyloid beta peptide interacts (colocalizes) with AKT1
1976 PDPK1 increases_phosphorylation of AKT1 at Thr308; phosphorylation at Ser473 is required for full Akt activity;
19144826 Alzheimer disease
427
1867 Amyloid beta peptide decreases_phosphorylation of AKT1 if AKT is insulin-induced;
1868 Amyloid beta peptide decreases_activity of AKT1 if AKT is insulin-induced;
1883 AKT1 interacts (colocalizes) with PDPK1
1884 AKT1 NOT interacts (colocalizes) with PDPK1 in presence of intraneuronal beta-amyloid and in presence of intracellular beta-amyloid(42);
2001 Amyloid beta peptide (42) decreases_activity of AKT1
2004 Amyloid beta peptide (42) decreases_phosphorylation of AKT1
19144826 Alzheimer disease
488
2302 Pioglitazone affects_phosphorylation of AKT1 in muscle
12446579 Diabetes mellitus, type II
Insulin resistance
598
3242 high-phytoestrogen soy-based diet affects_phosphorylation of AKT1 at Thr308/Ser473 of AKT1
18420492 Diabetes mellitus, type II
Obesity
Insulin resistance
622
3293 VEGFA increases_activity of AKT1 in spinal cord; in serum-deprived cultures
3300 VEGFA increases_phosphorylation of AKT1 in spinal cord; in serum-deprived cultures
19041930 Amyotrophic lateral sclerosis
627
3330 VEGFA increases_activity of AKT1 in spinal cord motoneurons
3331 VEGFA increases_phosphorylation of AKT1 in spinal cord motoneurons
18182045 Amyotrophic lateral sclerosis
654
3511 DGAT1 affects_activity of AKT1 in skeletal muscle; if stimulated by insulin
15569818 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
655
3497 (5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline) increases_activity of AKT1
3498 (5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline) increases_phosphorylation of AKT1 at Ser-473
3499 (5-[4-propargylpiperazin-1-ylmethyl]-8-hydroxyquinoline) increases_activity of AKT1
3500 (5-[4-propargylpiperazin-1-ylmethyl]-8-hydroxyquinoline) increases_phosphorylation of AKT1 at Ser-473
19638399 Amyotrophic lateral sclerosis
737
4157 6-OHDA decreases_phosphorylation of AKT1
18665912 Parkinson disease
792
4693 Alzheimer disease increases_quantity of AKT1
4695 AKT1 affects_expression of STUB1
4696 AKT1 increases_activity of MARK2
4697 AKT1 affects_phosphorylation of MAPT
19449461 Alzheimer disease
824
4800 AKT1 increases_phosphorylation of PPARGC1A in liver
4802 AKT1 decreases_quantity of PPARGC1A in liver; via increased degradation of PPARGC1A
4860 Insulin increases_activity of AKT1 in liver
4861 AKT1 increases_phosphorylation of CRTC2 in liver
4862 AKT1 increases_phosphorylation of PPARGC1A in liver
4863 AKT1 decreases_quantity of CRTC2 in liver; via increased degradation of CRTC2
4864 AKT1 decreases_quantity of PPARGC1A in liver; via increased degradation of PPARGC1A
4866 AKT1 decreases_activity of CRTC2 in liver
4867 AKT1 decreases_activity of PPARGC1A in liver
19770177 Diabetes mellitus, type II
Obesity
Insulin resistance
851
5063 response to oxidative stress increases_phosphorylation of AKT1 in the presence of DJ-1
5065 PARK7 increases_phosphorylation of AKT1 during oxidative stress
5073 AKT1 decreases_activity of neuron death in response to H2O2 and in the presence of DJ-1
5077 PARK7 increases_activity of AKT1
5081 AKT1 is localized in plasma membrane in response to H2O2 and in the presence of DJ-1
9725 AKT1 affects_activity of protein kinase B signaling
20133695 Parkinson disease
852
5071 PARK7 increases_phosphorylation of AKT1 in response to H2O2
5072 PARK7-p.L166P NOT increases_phosphorylation of AKT1 in response to H2O2
20133695 Parkinson disease
855
6308 PARK7 increases_phosphorylation of AKT1
15766664 Breast cancer
Parkinson disease
861
5106 AKT1 increases_phosphorylation of GSK3B at Ser9, thereby inactivating GSK3B;
5108 Alzheimer disease increases_quantity of AKT1
5117 AKT1 affects_phosphorylation of GSK3 at Ser9; this phosphorylated GSK3 is inactivated
5119 AKT1 increases_quantity of MAPT-hyperphos
19094 AKT1 affects_activity of protein kinase B signaling
12624792 Alzheimer disease
869
5147 Parkinson disease decreases_quantity of AKT1 in midbrain
5150 Parkinson disease decreases_phosphorylation of AKT1 in midbrain
19800394 Parkinson disease
871
5153 AKT1 decreases_activity of neuron death in PD mice
17116866 Parkinson disease
885
5213 EGF increases_phosphorylation of AKT1
5224 PARK2 NOT increases_phosphorylation of AKT1 in synaptosomes
16862145 Parkinson disease
921
5568 KDR increases_activity of AKT1
18178312 Amyotrophic lateral sclerosis
926
5607 EGF increases_phosphorylation of AKT1
5616 EGF increases_activity of AKT1
11445557 Amyotrophic lateral sclerosis
928
5611 SRC increases_activity of AKT1
5621 SRC increases_phosphorylation of AKT1
11445557 Amyotrophic lateral sclerosis
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