General Information:

Id: 97 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G93A transgenic mouse, transfected with human SOD1G93A, 60 days old
BTO:0000078 microglia
Reference: Weydt P et al.(2004) Increased cytotoxic potential of microglia from ALS-transgenic mice Glia 48: 179-182 [PMID: 15378658]

Interaction Information:

Comment Mutant superoxide dismutase (mtSOD1, G93A) expression increases the production of TNF-alpha and attenuates IL-6-release by LPS-activated adult microglia.
Formal Description
Interaction-ID: 318

gene/protein mutant


decreases_quantity of



in adult microglia; LPS stimulated
Drugbank entries Show/Hide entries for IL6