General Information:

Id: 933
Diseases: Alzheimer disease - [OMIM]
Mus musculus
BTO:0001976 Neuro-2a cell
Reference: Rezai-Zadeh K et al.(2005) Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice J. Neurosci. 25: 8807-8814 [PMID: 16177050]

Interaction Information:

Comment (-)-epigallocatechin-3-gallate (EGCG), the main polyphenolic constituent of green tea, reduces Abeta generation in murine neuron-like cells (N2a) transfected with the human Swedish mutant amyloid precursor protein (APP).
Formal Description
Interaction-ID: 5643

drug/chemical compound

Epigallocatechin 3-gallate

affects_quantity of


Amyloid beta peptide

in murine neuron-like cells (N2a)