General Information:

Id: 871
Diseases: Parkinson disease
Mus musculus
Reference: Ries V et al.(2006) Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinsons disease. Proc. Natl. Acad. Sci. U.S.A. 103 [PMID: 17116866]

Interaction Information:

Comment A constitutively active form of the oncoprotein Akt/PKB, the myristoylated AKT1, has been transduced into dopamine neurons of the substantia nigra of PD mice. This transduction confers almost complete protection against apoptotic cell death.
Formal Description
Interaction-ID: 5153



decreases_activity of


neuron death

in PD mice
Drugbank entries Show/Hide entries for AKT1