General Information:

Id: 6,979 (click here to show other Interactions for entry)
Diseases: Bardet-Biedl syndrome 16 - [OMIM]
Mus musculus
Reference: Airik R et al.(2016) SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling PLoS ONE 11 [PMID: 27224062]

Interaction Information:

Comment Sdccag8gt/gt mice exhibit developmental and structural abnormalities of the skeleton and limbs, suggesting impaired Hedgehog (Hh) signaling. Indeed, cell culture studies demonstrate the requirement of SDCCAG8 for ciliogenesis and Hh signaling.
Formal Description
Interaction-ID: 68532



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