General Information:

Id: 67 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Rattus norvegicus
BTO:0000991 pancreatic islet
Reference: Song MY et al.(2009) Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway. Toxicol. Appl. Pharmacol. 235: 57-67 [PMID: 19071154]

Interaction Information:

Comment Pretreatment with sulforaphane (SFN) blocked the effect of the cytokines and restored islet cell insulin secretion to levels similar to those in the controls.
Formal Description
Interaction-ID: 211

drug/chemical compound


increases_activity of

in pancreatic islets; in cytokine treated cells