General Information:

Id: 5,868 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Reference: Teperino R et al.(2014) Canonical and non-canonical Hedgehog signalling and the control of metabolism Semin. Cell Dev. Biol. 33: 81-92 [PMID: 24862854]

Interaction Information:

Comment Hedgehog signalling controls development of both endocrine and exocrine pancreas, as well as their function in adults. Furthermore, inappropriate activation of the pathway, alone or in combination with other oncogenes is associated with the development of pancreatic adenocarcinoma (PDAC).
Formal Description
Interaction-ID: 55492

affects_activity of

tissue/cell line

exocrine pancreas