General Information:

Id: 5,399 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Nephropathy, diabetic
Rattus norvegicus
Reference: Lin CL et al.(2008) Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway Am. J. Nephrol. 28: 290-297 [PMID: 18004065]

Interaction Information:

Comment Simvastatin restores cell survival and alleviates high glucose induced depression of Wnt/beta catenin signaling.
Formal Description
Interaction-ID: 52696

drug/chemical compound


increases_activity of

if decreased by high glucose
Drugbank entries Show/Hide entries for Simvastatin