General Information:

Id: 4,947
Diseases: Cardiovascular disease
Homo sapiens
Caucasians, African Americans
Reference: Gungor Z et al.(2012) Apo E4 and lipoprotein-associated phospholipase A2 synergistically increase cardiovascular risk Atherosclerosis 223: 230-234 [PMID: 22632920]

Interaction Information:

Comment The presence of the apo E4 isoform was associated with a higher level of Lp-PLA2 (PLA2G7, phospholipase A2, group VII) index, a marker of vascular inflammation. The Lp-PLA2 index, an integrated measure of Lp-PLA2 mass and activity was higher in apo E4 carriers irrespective of ethnicity.
Formal Description
Interaction-ID: 48906

gene/protein mutant

APOE (isoform E4)

increases_quantity of



in Caucasians and African Americans
Drugbank entries Show/Hide entries for PLA2G7