General Information:

Id: 457 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Reference: de la Monte SM(2009) Insulin resistance and Alzheimers disease BMB Rep 42: 475-481 [PMID: 19712582]

Interaction Information:

Comment GSK-3beta can be activated by oxidative stress, which is a consequence of insulin/IGF resistance and established feature of AD.
Formal Description
Interaction-ID: 2078

increases_activity of



Drugbank entries Show/Hide entries for GSK3B
Comment Induction of apoptosis is one of the possible responses to oxidative stress.
Formal Description
Interaction-ID: 36317