General Information:

Id: 427 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
BTO:0000165 C2C12 cell
Reference: Lee HK et al.(2009) The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid Mol. Biol. Cell 20: 1533-1544 [PMID: 19144826]

Interaction Information:

Comment The stimulated activity of Akt1 on the GSK substrate is markedly inhibited in the presence of intracellular beta-amyloid42.
Formal Description
Interaction-ID: 2001

decreases_activity of



concerning activity of Akt1 on the GSK substrate
Drugbank entries Show/Hide entries for AKT1