General Information:

Id: 421 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Caenorhabditis elegans
Reference: Samann J et al.(2009) Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth. J. Biol. Chem. 284 [PMID: 19251702]

Interaction Information:

Comment C. elegans pink1 mutant tm1779 displayed an increased sensitivity to a 3-day exposure to paraquat compared with wild type. Expression of transgenic pink-1 in pink-1(tm1779) mutants was sufficient to partially rescue the animals against paraquat-induced toxicity and other defects. This indicates that pink1 functions in oxidative stress response.
Formal Description
Interaction-ID: 1841



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