General Information:

Id: 4,212 (click here to show other Interactions for entry)
Diseases: Circadian rhythm
Wilson disease - [OMIM]
Rattus norvegicus
Reference: Borjigin J et al.(1999) A novel pineal night-specific ATPase encoded by the Wilson disease gene J. Neurosci. 19: 1018-1026 [PMID: 9920665]

Interaction Information:

Comment A pineal night-specific ATPase (PINA), a novel splice variant of the ATP7B gene is disrupted in Wilson disease (WD). PINA expression exhibits a dramatic diurnal rhythm in both pineal gland and retina with 100-fold greater expression at night than at day.
Formal Description
Interaction-ID: 43167

affects_expression of

mRNA/protein variant

ATP7B (PINA splice variant)

in penial gland and retina