General Information:

Id: 39 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Homo sapiens
NCI-H460 cell; BTO:0000007 HEK-293T cell
Reference: Yeung F et al.(2004) Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase EMBO J. 23: 2369-2380 [PMID: 15152190]

Interaction Information:

Comment SIRT1 inhibits NF-kappa-B transcription by directly deacetylating the RelA/p65 protein at lysine 310.
Formal Description
Interaction-ID: 93



decreases_activity of