General Information:

Id: 396 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G93A transgenic mouse, transfected with human SOD1G93A
BTO:0000099 astrocyte
Reference: Kiaei M et al.(2006) Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurosci. 26: 2467-2473 [PMID: 16510725]

Interaction Information:

Comment There is an increase of TNF-alpha and FasL immunoreactivity in lumbar spinal cord sections of ALS patients and G93A transgenic mice. TNF-alpha staining also occurred in actrocytes at 110 d of age.
Formal Description
Interaction-ID: 1638

gene/protein mutant


increases_quantity of



in astrocytes; at 110 days of age
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