General Information:

Id: 357 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Rattus norvegicus
BTO:0000138 midbrain
Reference: McCoy MK et al.(2006) Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinsons disease. J. Neurosci. 26: 9365-9375 [PMID: 16971520]

Interaction Information:

Comment TNF levels have been reported to increase in striatum and substantia nigra of 6-OHDA-injected rats.
Formal Description
Interaction-ID: 1417

drug/chemical compound


increases_quantity of



in striatum and substantia nigra
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