General Information:

Id: 3,388 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Carnitine deficiency, systemic primary - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Status epilepticus
Mammalia
review
Reference: Ringseis R et al.(2012) Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency Eur J Nutr 1: 1-18 [PMID: 22134503]

Interaction Information:

Comment In the JVS mouse model of primary carnitine deficiency hepatic transcript levels of glycolytic enzymes such as glucokinase and pyruvate kinase are reduced, whereas hepatic transcript level of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PCK1) is increased in this genetic model of carnitine deficiency.
Formal Description
Interaction-ID: 31850

phenotype

carnitine deficiency

increases_activity of

process

gluconeogenesis

in liver