General Information:

Id: 3,363 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
pre-diabetic Zucker diabetic fatty (ZDF) rats
Reference: Yi SS et al.(2010) Effects of hypothyroidism on cell proliferation and neuroblasts in the hippocampal dentate gyrus in a rat model of type 2 diabetes Anat Cell Biol 43: 185-193 [PMID: 21212858]

Interaction Information:

Comment Methimazole rescued the diabetes-induced reduction of Ki67- and DCX-immunoreactive cells. The rescue of cell proliferation and neuronal differentiation may be associated with the hypothyroidism-related reduction of corticosterone.
Formal Description
Interaction-ID: 30875

drug/chemical compound


affects_activity of

in the hippocampal dentate gyrus