General Information:

Id: 2,847 (click here to show other Interactions for entry)
Diseases: Cancer
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Reference: Ben Sahra I et al.(2008) The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level. Oncogene 27: 3576-3586 [PMID: 18212742]

Interaction Information:

Comment The antiproliferative effect of metformin is not mediated by the AMPK-pathway.
Formal Description
Interaction-ID: 26237

drug/chemical compound


decreases_activity of

not via AMPK signaling pathway
Drugbank entries Show/Hide entries for Metformin