General Information:

Id: 2,689 (click here to show other Interactions for entry)
Diseases: Endocrine
Postpartum depression
Mus musculus
BTO:0000007 HEK-293 cell
Reference: Schreiber SN et al.(2003) The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha). J. Biol. Chem. 278: 9013-9018 [PMID: 12522104]

Interaction Information:

Comment PGC-1 interacts physically with ERRalpha and enables it to activate transcription. PGC-1 converts ERRalpha from a factor with little or no transcriptional activity to a potent regulator of gene expression (potentially associated with postpartum depression).
Formal Description
Interaction-ID: 25171



increases_activity of



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