General Information:

Id: 1,989 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Myocardial infarction - [OMIM]
Nephropathy, diabetic
Neuropathy, diabetic
Retinopathy, diabetic
Stroke, ischemic - [OMIM]
Reference: Lardizabal JA and Deedwania PC(2010) The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus Curr Cardiol Rep 12: 464-471 [PMID: 20809236]

Interaction Information:

Comment The protection afforded by ARBs against the deleterious effects of inflammatory and oxidative stress was associated with increased beta-cell mass, augmented insulin secretion, and improved glucose tolerance. Furthermore, ARB therapy was also shown to prevent the loss of endothelial cells and reduce fibrosis in and around the islets.
Formal Description
Interaction-ID: 15692

drug/chemical compound

Angiotensin II type 1 receptor blocker

decreases_activity of